AFP Protein (His Tag), recombinant mouse

Activity: Immunogen(E-AB-40293) Protein Construction: A DNA sequence encoding the Mouse AFP (P02772-1) (Tyr273-Val605) was expressed with a polyhistidine tag at the N-terminus. Sequence: Tyr273-Val605. Fusion tag: N-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 28.2kDa. Protein function: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Protein function: Binds estrogens, fatty acids and metals. [The UniProt Consortium]