ACE2 Protein (His Tag), recombinant Human

Measured by its binding ability in a functional ELISA.Immobilized Recombinant 2019-nCoV Spike Protein (RBD, mFc Tag)(PKSR030500) at 2µg/mL (100µL/well) can bind human ACE2 protein (PKSR030510),the EC50 of Recombinant Human ACE2 Protein (His Tag) (PKSR030510) is 10-35ng/mL. Fusion tag:C-6His NP_068576.1 Met1-Ser740 Protein function: Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator (PubMed:10969042, PubMed:10924499, PubMed:11815627). Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency (PubMed:11815627). By cleavage of angiotensin II, may be an important regulator of heart function (PubMed:10969042, PubMed:10924499). By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity (PubMed:18424768, PubMed:19185582). [The UniProt Consortium]