HUMAN TTK Peptide Pool

Pool of 212 overlapping peptides derived from a peptide scan (15mers with 11 aa overlap) through Dual specificity protein kinase TTK (UniProtKB - P33981) of homo sapiens. One unit allows the stimulation of 2,5 x 10^8 cells.You can find applications and references in our blog post: Esophagogastric adenocarcinoma: Tumor-associated antigens, immune responses and HLA-I Expression Protein function: Phosphorylates proteins on serine, threonine, and tyrosine (PubMed:18243099, PubMed:29162720). Probably associated with cell proliferation (PubMed:18243099). Phosphorylates MAD1L1 to promote mitotic checkpoint signaling (PubMed:29162720). Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint (PubMed:18243099). [The UniProt Consortium]