sn-glycero-3-Phosphocholine

sn-glycero-3-Phosphocholine (sn-glycero-3-PC) is a nootropic phospholipid, a precursor to choline biosynthesis, and an intermediate in the metabolism of phosphatidylcholine. In vivo, sn-glycero-3-PC is converted to phosphorylcholine, a metabolically active form of choline that increases acetylcholine synthesis and release in rat hippocampus. It prevents scopolamine-induced amnesia in a passive avoidance test in rats and exerts neuroprotective effects in models of altered cholinergic neurotransmission and models of brain vascular injury.Formal Name: 2-[[[(2R)-2,3-dihydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-ethanaminium, inner salt. CAS Number: 28319-77-9. Synonyms: Glycerophosphocholine, L-alpha-GPC, L-alpha-Glycerylphosphorylcholine, sn-glycero-3-PC. Molecular Formula: C8H20NO6P. Formula Weight: 257.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Ethanol: 1 mg/mL, PBS (pH 7.2): 3 mg/mL. SMILES: OC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O. InChi Code: InChI=1S/C8H20NO6P/c1-9(2,3)4-5-14-16(12,13)15-7-8(11)6-10/h8,10-11H,4-7H2,1-3H3/t8-/m1/s1. InChi Key: SUHOQUVVVLNYQR-MRVPVSSYSA-N.