Silybin

Silybin is the major flavonolignan found in milk thistle (S. marianum). It inhibits wild mushroom tyrosinase (IC50 = 1.7 µM). Silybin scavenges superoxide radicals (IC50 = 55.2 µM) and inhibits lipid peroxidation in vitro (IC50 = 73.92 µM).Formal Name: (2R,3R)-2-[(2R,3R)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one. CAS Number: 22888-70-6. Synonyms: Silibinin, Silibinin A, Silybin A. Molecular Formula: C25H22O10. Formula Weight: 482.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMF:PBS (pH 7.2)(1:9): .5 mg/ml, DMSO: 10 mg/ml, Ethanol: .1 mg/ml. lambdamax: 229, 288 nm. SMILES: OC1=CC(O)=CC(O[C@H](C2=CC3=C(O[C@H](CO)[C@@H](C4=CC(OC)=C(O)C=C4)O3)C=C2)[C@H]5O)=C1C5=O. InChi Code: InChI=1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3/t20-,23+,24-,25-/m1/s1. InChi Key: SEBFKMXJBCUCAI-HKTJVKLFSA-N. Origin: Synthetic.