Leukotriene B4 dimethyl amide

LTB4 dimethyl amide is a moderate inhibitor of LTB4-induced degranulation of human neutrophils (Ki = 130 nM) and lysozyme release from rat PMNL. LTB4 dimethyl amide appears to be an antagonist of the LTB4 receptor on guinea pig lung membranes.Formal Name: N,N-dimethyl-5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenamide. CAS Number: 83024-92-4. Synonyms: LTB4 dimethyl amide. Molecular Formula: C22H37NO3. Formula Weight: 363.5. Purity: >97%. Formulation: (Request formulation change), A solution in methanol. Solubility: DMF: >50 mg/ml, DMSO: >50 mg/ml, Ethanol: >50 mg/ml, PBS pH 7.2: >1 mg/ml. lambdamax: 270 nm. SMILES: CCCCC/C=C\C[C@@H](O)/C=C/C=C\C=C\[C@@H](O)CCCC(=O)N(C)C. InChi Code: InChI=1S/C22H37NO3/c1-4-5-6-7-8-11-15-20(24)16-12-9-10-13-17-21(25)18-14-19-22(26)23(2)3/h8-13,16-17,20-21,24-25H,4-7,14-15,18-19H2,1-3H3/b10-9+,11-8-,16-12+,17-13-/t20-,21-/m1/s1. InChi Key: BBJRTSLPWQUASB-UKODYPNASA-N.