DDA

Lipoxygenase-catalyzed peroxidative decomposition of unsaturated fatty acids occurs within seconds when diatoms are crushed or eaten, producing alkyls. DDA is a prominent member of this class of reactive compounds. Common omega-6 fatty acids such as linoleic acid, dihomo-omega-linolenic acid, and arachidonic acid can give rise to DDA. DDA reduces the hatching rate and has a strong teratogenic effect on the eggs of pelagic copepods, at concentrations around 1 µM. In human carcinoma Caco2 cells, DDA induces cell growth arrest at around 15 µM. DDA appears to be a natural defensive chemical designed to limit the reproductive success of copepods, the main predators of diatoms. It may also be a more general inducer of apoptosis.Formal Name: 2E,4E-decadienal. CAS Number: 25152-84-5. Synonyms: Decadienealdehyde, trans-2,4-Decadien-1-al. Molecular Formula: C10H16O. Formula Weight: 152.2. Purity: >98%. Formulation: (Request formulation change), A liquid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml, Ethanol:PBS (pH 7.2) (1:2): .15 mg/ml. lambdamax: 273 nm. SMILES: CCCCC\C=C\C=C/C=O. InChi Code: InChI=1S/C10H16O/c1-2-3-4-5-6-7-8-9-10-11/h6-10H,2-5H2,1H3/b7-6+,9-8+. InChi Key: JZQKTMZYLHNFPL-BLHCBFLLSA-N. Origin: Synthetic.