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N-3-oxo-dodecanoyl-L-Homoserine lactone
Artikelnummer: Cay10007895-1
N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex. It induces the production of IL-8 in 16HBE human bronchial epithelial cells when used at a concentration of 100 µM. Supernatants from...
| Schlagworte: | 3-oxo-C12-HSL, N-(3-oxododecanoyl) L-Homoserine lactone, 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-dodecanamide |
| Anwendung: | Bioactive lipid assays |
| CAS | 168982-69-2 |
| MW: | 297.4 D |
ab 44,00 €
Prostaglandin E2-d4
Artikelnummer: Cay314010-50
Prostaglandin E2-d4 (PGE2-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGE2 by GC- or LC-mass spectrometry. PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated...
| Schlagworte: | Dinoprostone-d4, PGE2-d4, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid |
| Anwendung: | Standard |
| CAS | 34210-10-1 |
| MW: | 356.5 D |
ab 89,00 €
FTY720 Phosphate
Artikelnummer: Cay10008639-1
FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. In vivo, FTY720...
| Schlagworte: | FTY720P, 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol, 1-(dihydrogen phosphate) |
| Anwendung: | Sphingosine analog |
| CAS | 402615-91-2 |
| MW: | 387.5 D |
ab 142,00 €
Resolvin D2
Artikelnummer: Cay10007279-10
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D2 (RvD2) is produced...
| Schlagworte: | 7(S),16(R),17(S)-Resolvin D2, RvD2, 7S,16R,17S-trihydroxy-4Z,8E,10Z,12E,14E,19Z-docosahexaenoic acid |
| Anwendung: | Lipid mediator |
| CAS | 810668-37-2 |
| MW: | 376.5 D |
ab 205,00 €
2-Arachidonoyl Glycerol
Artikelnummer: Cay62160-1
2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the cannabinoid (CB) receptors CB1 and CB2 (Kis = 25.3-472 and 145-1,400 nM, respectively). Unlike arachidonoyl ethanolamide (AEA, Cay-90050), 2-AG is present at relatively high levels in the central nervous system and is the most abundant molecular species...
| Schlagworte: | 2-AG, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glyceryl ester |
| Anwendung: | CB1 receptor agonist |
| CAS | 53847-30-6 |
| MW: | 378.6 D |
ab 50,00 €
4-hydroxy Nonenal
Artikelnummer: Cay32100-1
4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized omega-6 polyunsaturated fatty acids such as arachidonic acid. 4-hydroxy Nonenal is widely used as a marker of lipid peroxidation. It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and...
| Schlagworte: | 4-HNE, (±)-4-hydroxy-2E-nonenal |
| Anwendung: | Lipid peroxidation studies |
| CAS | 75899-68-2 |
| MW: | 156.2 D |
ab 105,00 €
20-HETE
Artikelnummer: Cay90030-50
20-HETE is a cytochrome P450 (CYP450) metabolite postulated to play an autacoid role in the renal and cerebral vasculature. In rat cerebral microvessels, 20-HETE is a vasoconstrictor that mediates pressure-induced autoregulatory vasoconstriction. 20-HETE is excreted mainly as the glucuronide conjugate. The...
| Schlagworte: | 20-hydroxy Arachidonic Acid, 20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Anwendung: | Bioactive lipid assays |
| CAS | 79551-86-3 |
| MW: | 320.5 D |
ab 217,00 €
Prostaglandin B1
Artikelnummer: Cay11110-1
Prostaglandin B1 (PGB1) is a non-enzymatic dehydration product of PGE1 resulting from treatment with strong base. Oligomers of PGB1 are known to exhibit antioxidant and ionophoric activity.Formal Name: 9-oxo-15S-hydroxy-prosta-8(12),13E-dien-1-oic acid. CAS Number: 13345-51-2. Synonyms: PGB1. Molecular Formula:...
| Schlagworte: | PGB1, 9-oxo-15S-hydroxy-prosta-8(12),13E-dien-1-oic acid |
| Anwendung: | Bioactive lipid assays |
| CAS | 13345-51-2 |
| MW: | 336.5 D |
ab 34,00 €
Arachidonic Acid (peroxide free)
Artikelnummer: Cay90010.1-100
Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient,...
| Schlagworte: | AA (peroxide free), 5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Anwendung: | Bioactive lipid assays |
| CAS | 506-32-1 |
| MW: | 304.5 D |
ab 50,00 €
Leukotriene B4-d4
Artikelnummer: Cay320110-25
Leukotriene B4-d4 (LTB4-d4) is intended for use as an internal standard for the quantification of LTB4 (Cay-20110) by GC- or LC-MS. LTB4 is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion...
| Schlagworte: | LTB4-d4, 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic-6,7,14,15-d4 acid |
| Anwendung: | Standard |
| CAS | 124629-74-9 |
| MW: | 340.5 D |
ab 410,00 €
Thromboxane B2
Artikelnummer: Cay19030-1
Thromboxane B2 (TXB2) is a non-enzymatically derived, stable, inactive metabolite of TXA2, which is highly unstable. Serum levels of TXB2 positively correlate with platelet COX-1 activation. Urinary levels of TXB2 reflect intrarenal TXA2 synthesis, while its metabolites, 11-dehydro TXB2 (Cay-19500) and 2,3-dinor...
| Schlagworte: | TXB2, 9alpha,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid |
| Anwendung: | Bioactive lipid assays |
| CAS | 54397-85-2 |
| MW: | 370.5 D |
ab 121,00 €
12(S)-HETE
Artikelnummer: Cay34570-25
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.Formal Name: 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid. CAS Number: 54397-83-0. Synonyms: 12(S)-Hydroxyeicosatetraenoic Acid....
| Schlagworte: | 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid |
| Anwendung: | Bioactive lipid assays |
| CAS | 54397-83-0 |
| MW: | 320.5 D |
ab 189,00 €