13,14-epoxy Fluprostenol isopropyl ester

Fluprostenol isopropyl ester (Cay-16769) is a potent F-series prostaglandin receptor agonist that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma. 13,14-epoxy Fluprostenol isopropyl ester is an impurity generated in the production of fluprostenol isopropyl ester. This product is a 4:96 diastereomeric mixture of epoxides.Formal Name: 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(2R)-3-[(1S)-1-hydroxy-2-[3-(trifluoromethyl)phenoxy]ethyl]-2-oxiranyl]cyclopentyl]-5-heptenoic acid, 1-methylethyl ester. CAS Number: 2557327-99-6. Synonyms: 13,14-epoxy Travoprost. Molecular Formula: C26H35F3O7. Formula Weight: 516.6. Purity: >95% (epoxide mixture). Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 30 mg/ml, DMSO: 5 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 222, 276 nm. SMILES: O[C@@H]1C[C@H](O)[C@H](C/C=C\CCCC(OC(C)C)=O)[C@H]1[C@@H](O2)C2[C@@H](O)COC3=CC=CC(C(F)(F)F)=C3. InChi Code: InChI=1S/C26H35F3O7/c1-15(2)35-22(33)11-6-4-3-5-10-18-19(30)13-20(31)23(18)25-24(36-25)21(32)14-34-17-9-7-8-16(12-17)26(27,28)29/h3,5,7-9,12,15,18-21,23-25,30-32H,4,6,10-11,13-14H2,1-2H3/b5-3-/t18-,19-,20+,21-,23+,24?,25+/m0/s1. InChi Key: BGPCWSPTSAFVAF-LCEFRZHDSA-N.