1-Oleyl-2-hydroxy-sn-glycero-3-PA (sodium salt)

1-Oleyl-2-hydroxy-sn-glycero-3-PA (1-Octadecyl LPA) is a LPA analog containing stearyl alcohol at the sn-1 position. LPA binds to one of five different G protein-linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has platelet aggregating activity with an EC50 value of 9 nM versus an EC50 value of 177 nM for 1-octadecanoyl LPA.Formal Name: 1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate, monosodium salt. Synonyms: LPA O-18:0, O-18:0 LPA, 1-Octadecyl-2-hydroxy-sn-glycero-3-phosphate, 1-Octadecyl LPA, 1-Octadecyl Lysophosphatidic Acid, 1-Oleyl LPA, 1-Oleyl Lysophosphatidic Acid, PA(O-18:0/0:0). Molecular Formula: C21H44O6P . Na. Formula Weight: 446.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. SMILES: O[C@@H](COP([O-])(O)=O)COCCCCCCCCCCCCCCCCCC.[Na+]. InChi Code: InChI=1S/C21H45O6P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-26-19-21(22)20-27-28(23,24)25,/h21-22H,2-20H2,1H3,(H2,23,24,25),/q,+1/p-1/t21-,/m1./s1. InChi Key: FYSJNCTWZSVDDQ-ZMBIFBSDSA-M. Side Chain Carbon Sum: 18:0.