Tide Fluor(TM) 7 amine [TF7 amine] *Superior replacement to Cy7*

Tide Fluor(TM)7 (TF7) family has the spectral properties similar to those of Cy7, IRDye 800 and Alexa Fluor 750. Their fluorescence is pH-independent from pH 3 to 11. These characteristics make this new dye family more robust to pH-sensitive assays. In some cases TF7-labeled peptides and nucleotides exhibit stronger fluorescence and higher photostability than the ones labeled with Cy7, IRDye 800 and Alexa Fluor 750. In pairing with our Tide Quencher(TM) 7 (TQ7), a variety of FRET peptides and nucleotides can be developed for detecting proteases and molecular beacons with enhanced sensitivity and stability.