Tide Fluor(TM) 5 alkyne (TF5 alkyne)

Tide Fluor(TM) 5 (TF5) family has the spectral properties essentially identical to those of Cy5. Compared to Cy5 probes TF5 family has much stronger fluorescence and higher photostability. Additionally their fluorescence is pH-independent from pH 3 to 11. These characteristics make this new dye family a superior alternative to Cy5. TF5-labeled peptides and nucleotides exhibit much stronger fluorescence and higher photostability than the ones labeled with Cy5. In pairing with our Tide Quencher(TM) 5 (TQ5), a variety of FRET peptides and nucleotides can be developed for detecting proteases and molecular beacons with enhanced sensitivity and stability. This TF5 product is reactive to azides, and useful for click chemistry.