Triamterene-d5

Triamterene-d5 is intended for use as an internal standard for the quantification of triamterene (Cay-21242) by GC- or LC-MS. Triamterene is an inhibitor of the epithelial sodium channel (ENaC, IC50 = 4.5 µM for the rat channel). In vivo, triamterene (0.5-32 mg/animal) enhances sodium secretion and decreases potassium secretion in adrenalectomized rats. Formulations containing triamterene have been used in the treatment of edema.Formal Name: 6-phenyl-d5-2,4,7-pteridinetriamine. CAS Number: 1189922-23-3. Synonyms: 2,4,7-Triamino-6-phenylpteridine-d5. Molecular Formula: C12H6D5N7. Formula Weight: 258.3. Purity: >99% deuterated forms (d1-d5). Formulation: (Request formulation change), A solid. Solubility: DMSO: slightly soluble, Methanol: slightly soluble. SMILES: NC1=NC(N)=NC2=C1N=C(C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])C(N)=N2. InChi Code: InChI=1S/C12H11N7/c13-9-7(6-4-2-1-3-5-6)16-8-10(14)18-12(15)19-11(8)17-9/h1-5H,(H6,13,14,15,17,18,19)/i1D,2D,3D,4D,5D. InChi Key: FNYLWPVRPXGIIP-RALIUCGRSA-N.