ST638

ST638 is a tyrosine kinase inhibitor (IC50 = 370 nM). It suppresses tyrosine phosphorylation induced by tumor necrosis factor-alpha and phorbol myristate acetate in neutrophils and by angiotensin II in cardiac fibroblasts.Formal Name: 2-cyano-3-[3-ethoxy-4-hydroxy-5-[(5-phenylthio)methyl]phenyl]-2-propenamide. CAS Number: 107761-24-0. Molecular Formula: C19H18N2O3S. Formula Weight: 354.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 50 mg/ml, DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml, DMSO: 30 mg/ml. lambdamax: 252, 363 nm. SMILES: OC1=C(C=C(C=C(C(N)=O)C#N)C=C1OCC)CSC2=CC=CC=C2. InChi Code: InChI=1S/C19H18N2O3S/c1-2-24-17-10-13(8-14(11-20)19(21)23)9-15(18(17)22)12-25-16-6-4-3-5-7-16/h3-10,22H,2,12H2,1H3,(H2,21,23). InChi Key: YKLMGKWXBLSKPK-UHFFFAOYSA-N.