Physcion

Physcion is a natural anthraquinone. It has been reported to have laxative and anti-inflammatory actions, inhibit kinases and tyrosinase, and have cytotoxicity against cancer cells. Physcion inhibits 6-phosphogluconate dehydrogenase (IC50 = 38.5 µM), decreasing lipogenesis and RNA biosynthesis in cancer cells, leading to reduced cell proliferation and tumor growth in mice.Formal Name: 1,8-dihydroxy-3-methoxy-6-methyl-9,10-anthracenedione. CAS Number: 521-61-9. Synonyms: 6-O-methyl Emodin, NSC 251670. Molecular Formula: C16H12O5. Formula Weight: 284.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. lambdamax: 223, 266, 286, 434 nm. SMILES: CC1=CC2=C(C(O)=C1)C(C3=C(O)C=C(OC)C=C3C2=O)=O. InChi Code: InChI=1S/C16H12O5/c1-7-3-9-13(11(17)4-7)16(20)14-10(15(9)19)5-8(21-2)6-12(14)18/h3-6,17-18H,1-2H3. InChi Key: FFWOKTFYGVYKIR-UHFFFAOYSA-N.