Lathosterol

Lathosterol is an intermediate in the biosynthesis of cholesterol. Serum levels of lathosterol correlate with cholesterol synthesis and have been used as biomarkers of excess cholesterol production. Lathosterol accumulates in lathosterolosis, a disorder characterized by a deficiency of lathosterol 5-desaturase, the enzyme that converts lathosterol to 7-dehydro cholesterol (Cay-14612).Formal Name: 5alpha-cholest-7-en-3beta-ol. CAS Number: 80-99-9. Synonyms: Delta7-Cholestenol, gamma-Cholestenol. Molecular Formula: C27H46O. Formula Weight: 386.7. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 2 mg/ml, DMSO: 0.1 mg/ml, Ethanol: 20 mg/ml, Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml. lambdamax: 210, 272, 282 nm. SMILES: CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]2([H])C3=CC[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C. InChi Code: InChI=1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h10,18-21,23-25,28H,6-9,11-17H2,1-5H3/t19-,20+,21+,23-,24+,25+,26+,27-/m1/s1. InChi Key: IZVFFXVYBHFIHY-SKCNUYALSA-N.