L-Leu-AMC (hydrochloride)

L-Leu-AMC is a fluorogenic substrate for leucine aminopeptidase. Upon enzymatic cleavage by leucine aminopeptidase, AMC is released and its fluorescence can be used to quantify leucine aminopeptidase activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.Formal Name: (2S)-2-amino-4-methyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-pentanamide, monohydrochloride. CAS Number: 62480-44-8. Synonyms: Leu-MCA, L-Leucine-7-amido-4-methylcoumarin, 7-L-Leucyl-4-methylcoumarinylamide. Molecular Formula: C16H20N2O3 . HCl. Formula Weight: 324.8. Purity: >98%. Emission: 440-460 nm. Excitation: 340-360 nm. Formulation: (Request formulation change), A solid. Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml, DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml. lambdamax: 214, 296, 326 nm. SMILES: CC(C1=CC=C(NC([C@@H](N)CC(C)C)=O)C=C1O2)=CC2=O.Cl. InChi Code: InChI=1S/C16H20N2O3.ClH/c1-9(2)6-13(17)16(20)18-11-4-5-12-10(3)7-15(19)21-14(12)8-11,/h4-5,7-9,13H,6,17H2,1-3H3,(H,18,20),1H/t13-,/m0./s1. InChi Key: VCRXITKKWBOQRZ-ZOWNYOTGSA-N.