Hydrocupreine

Hydrocupreine (6'-Hydroxydihydrocinchonidine) is a derivative of cinchonidine and metabolite of quinine, alkaloids found in the bark of the Cinchona tree. It has been shown to have antimicrobial and antitumor activity, and inhibitory effect on Trypanosoma brucei and Streptococcus pneumoniae. Hydrocupreine can be used as a building block, starting material or reagent in organic synthesis to create more complex chiral chemical compounds and/or azo dyes. It has been used in organocatalaysis and during Friedel-Crafts amination.