Exo1

Exo1 is a cell-permeable, reversible inhibitor of exocytosis (IC50 = 20 µM). It interferes with protein trafficking and secretion mediated by the Golgi apparatus and endoplasmic reticulum by dissociating the GTPase activator ADP-ribosylation factor (ARF1) from Golgi membranes, which leads to a consequent collapse of the Golgi apparatus.Formal Name: 2-[(4-fluorobenzoyl)amino]-benzoic acid, methyl ester. CAS Number: 75541-83-2. Synonyms: Exocytic Inhibitor 1, NSC 214045. Molecular Formula: C15H12FNO3. Formula Weight: 273.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 100 mM, Ethanol: 25 mM. lambdamax: 235, 267, 314 nm. SMILES: O=C(OC)C1=CC=CC=C1NC(C2=CC=C(F)C=C2)=O. InChi Code: InChI=1S/C15H12FNO3/c1-20-15(19)12-4-2-3-5-13(12)17-14(18)10-6-8-11(16)9-7-10/h2-9H,1H3,(H,17,18). InChi Key: KIAPWMKFHIKQOZ-UHFFFAOYSA-N.