Brevetoxin 3

Artikelnummer	Größe	Manual	Lieferzeit	Preis
LKT-B6918.100	100 µg	-	3 - 8 Werktage*	862,00 €
LKT-B6918.1	1 mg	-	3 - 8 Werktage*	7.342,00 €
LKT-B6918.5	5 mg	-	3 - 8 Werktage*	23.006,00 €

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Brevetoxins are lipid-soluble polyether neurotoxins produced by the dinoflagellate Karenia... mehr

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Produktinformationen "Brevetoxin 3"

Brevetoxins are lipid-soluble polyether neurotoxins produced by the dinoflagellate Karenia brevis. Brevetoxins act as agonists, binding the neurotoxin site 5 on SCN4A/Nav1.4 and SCN5A/Nav1.5 voltage-gated Na+ channels in skeletal muscle and cardiac tissue, producing a channel opening effect, this activity results in bronchoconstriction and airway inflammation in vivo. Stimulation of the voltage-gated Na+ channels also induces NMDA receptor-mediated release of L-glutamate and L-aspartate in neurons. Brevetoxin 3 is a type B brevetoxin and a metabolite of brevetoxin 2.

Schlagworte:	PbTx-3
Hersteller:	LKT Laboratories
Hersteller-Nr:	B6918

Eigenschaften

Anwendung:	SCN4A/Nav1.4 / SCN5A/Nav1.5 agonist
MW:	897.2 D
Reinheit:	>95%
Format:	Solid

Datenbank Information

CAS :	85079-48-7\| Passende Produkte
KEGG ID :	K04837 \| Passende Produkte

Handhabung & Sicherheit

Lagerung:	+20°C
Versand:	+20°C (International: +20°C)
Signalwort:	Danger
GHS-Piktogramme:
H-Sätze:	H300, H310, H330
P-Sätze:	P260, P262, P264, P270, P271, P280, P284, P301+P310, P302+P352, P304+340, P310, P312, P320, P330, P361, P363, P403+233, P405, P501