Aspalatone

Aspalatone is an anti-platelet aggregator (IC50 = 180 µM, in vitro) that prolongs bleeding time significantly in a rodent model of thromboembolism. Additionally at a minimal effective dose of 24 mg/kg, aspalatone generates antioxidant and neuroprotective effects against kainic acid-induced epilepsy in rat hippocampus.Formal Name: 2-(acetyloxy)-2-methyl-4-oxo-4H-pyran-3-yl-benzoic acid ester. CAS Number: 147249-33-0. Synonyms: Acetylsalicylic Acid Matol ester. Molecular Formula: C15H12O6. Formula Weight: 288.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml, Ethanol: 1 mg/ml. lambdamax: 237 nm. SMILES: O=C1C(OC(C2=C(OC(C)=O)C=CC=C2)=O)=C(C)OC=C1. InChi Code: InChI=1S/C15H12O6/c1-9-14(12(17)7-8-19-9)21-15(18)11-5-3-4-6-13(11)20-10(2)16/h3-8H,1-2H3. InChi Key: JVBIZYPCGNCWIT-UHFFFAOYSA-N.