2',3'-cyclic NADP+ (sodium salt)

2',3'-cyclic NADP+ is a substrate for 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP), an enzyme that is abundant in myelin. It has been used in coupled enzyme assays to quantify CNP activity. 2',3'-cyclic NADP+ (5 µM) increases calcium overload-induced calcium release and prevents calcium-induced swelling in rat brain mitochondria.Formal Name: cyclic 2',3'-(hydrogen phosphate) adenosine 5'-(trihydrogen diphosphate), P'->5'-ester with 3-(aminocarbonyl)-1-beta-D-ribofuranosylpyridinium, inner salt, disodium salt. CAS Number: 100929-77-9. Synonyms: 2',3'-cNADP+, beta-Nicotinamide adenine dinucleotide-2',3'-cyclic phosphate. Molecular Formula: C21H24N7O16P3 . 2Na. Formula Weight: 769.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: Soluble. SMILES: O[C@H]([C@@H]1O)[C@H]([N+]2=CC(C(N)=O)=CC=C2)O[C@@H]1COP([O-])(OP([O-])(OC[C@H]([C@]3([H])[C@@]4([H])OP(O3)([O-])=O)O[C@H]4N5C=NC6=C(N)N=CN=C65)=O)=O.[Na+].[Na+]. InChi Code: InChI=1S/C21H26N7O16P3.2Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16-15(42-47(36,37)43-16)11(41-21)6-39-46(34,35)44-45(32,33)38-5-10-13(29)14(30)20(40-10)27-3-1-2-9(4-27)18(23)31,,/h1-4,7-8,10-11,13-16,20-21,29-30H,5-6H2,(H6-,22,23,24,25,31,32,33,34,35,36,37),,/q,2*+1/p-2/t10-,11-,13-,14-,15-,16-,20-,21-,,/m1../s1. InChi Key: REJNCHGXPBLANE-WUEGHLCSSA-L.