2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide

2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is an antimicrobial agent. It is active against the Gram-negative bacteria E. coli, P. aeruginosa, and S. marcescens (MICs = 64, 100, and 70 µg/ml, respectively), the Gram-positive bacteria S. aureus, M. luteus, and B. cereus (MICs = 130, 100, and 50 µg/ml, respectively), and the fungi C. albicans, G. candidum, T. rubrum, F. oxysporum, A. flavus, and S. brevicaulis (MICs = 69-120 µg/ml). 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is also a precursor in the synthesis of other antimicrobial agents, as well as compounds with anticancer activity.Formal Name: 2-[1-(2-thienyl)ethylidene]-hydrazinecarbothioamide. CAS Number: 5351-71-3. Synonyms: NSC 707, 1-(Thiophen-2-yl)ethanone thiosemicarbazone. Molecular Formula: C7H9N3S2. Formula Weight: 199.3. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:4): 0.20 mg/ml, Ethanol: 1 mg/ml. lambdamax: 248, 327 nm. SMILES: S=C(N/N=C(C)/C1=CC=CS1)N. InChi Code: InChI=1S/C7H9N3S2/c1-5(9-10-7(8)11)6-3-2-4-12-6/h2-4H,1H3,(H3,8,10,11)/b9-5+. InChi Key: PJVHAJJEMJNPHN-WEVVVXLNSA-N.