Deoxyenterocin

Deoxyenterocin is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities, including antibiotic, antiviral, and antioxidant properties. It inhibits the growth of S. lutea, S. aureus, K. pneumoniae, and V. percolans in vitro when used at a concentration of 500 µg/ml. Deoxyenterocin (50 µg/ml) inhibits the cytopathic effect of influenza A H1N1 virus by 60.6% in vitro. It also prevents hydrogen peroxide-induced decreases in glutathione (GSH) levels and in the mitochondrial membrane potential in mouse primary cortical neuronal cultures when used at a concentration of 1 µM.Formal Name: (3S,4aR,5S,6S,7S,7aS)-7-benzoylhexahydro-4a,6,7a-trihydroxy-5-(4-methoxy-2-oxo-2H-pyran-6-yl)-3,6-methanocyclopenta[c]pyran-1(3H)-one. CAS Number: 108605-51-2. Synonyms: 5-Deoxyenterocin. Molecular Formula: C22H20O9. Formula Weight: 428.4. Purity: >99%. Formulation: (Request formulation change), A solid. Solubility: DMF: soluble, DMSO: soluble, Ethanol: soluble, Methanol: soluble. SMILES: O=C1[C@@]2(O)[C@@]([C@@H](C(O3)=CC(OC)=CC3=O)[C@]4(O)[C@@H]2C(C5=CC=CC=C5)=O)(O)C[C@@](C4)([H])O1. InChi Code: InChI=1S/C22H20O9/c1-29-12-7-14(31-15(23)8-12)17-20(26)9-13-10-21(17,27)22(28,19(25)30-13)18(20)16(24)11-5-3-2-4-6-11/h2-8,13,17-18,26-28H,9-10H2,1H3/t13-,17-,18-,20-,21+,22+/m0/s1. InChi Key: UTKCEZMWSNDCMR-SAKMHLFVSA-N. Origin: Bacterium/Streptomyces sp..