Cefpirome (sulfate)

Cefpirome is a cephalosporin antibiotic. It is active against clinical isolates of various bacteria, including K. pneumoniae, E. aerogenes, Salmonella, and Shigella (MIC50s = 0.06, 0.12, 0.06, and 0.06 µg/ml, respectively). Cefpirome protects non-leukopenic mice from systemic bacterial infections induced by E. coli, S. aureus, or S. marcescens (ED50s = 0.76, 1.1, and 7.5 mg/kg, respectively).Formal Name: 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-6,7-dihydro-5H-cyclopenta[b]pyridinium, monosulfate. CAS Number: 98753-19-6. Synonyms: HR 810. Molecular Formula: C22H23N6O5S2 . HSO4. Formula Weight: 612.7. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 1 mg/ml, DMSO: 10 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 272 nm. SMILES: O=S(O)([O-])=O.CO/N=C(C1=CSC(N)=N1)\C(N[C@H]2[C@](SCC(C[N+]3=C4C(CCC4)=CC=C3)=C5C(O)=O)([H])N5C2=O)=O. InChi Code: InChI=1S/C22H22N6O5S2.H2O4S/c1-33-26-15(13-10-35-22(23)24-13)18(29)25-16-19(30)28-17(21(31)32)12(9-34-20(16)28)8-27-7-3-5-11-4-2-6-14(11)27,1-5(2,3)4/h3,5,7,10,16,20H,2,4,6,8-9H2,1H3,(H3-,23,24,25,29,31,32),(H2,1,2,3,4)/b26-15-,/t16-,20-,/m1./s1. InChi Key: RKTNPKZEPLCLSF-QHBKFCFHSA-N.