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Gli Reporter - NIH3T3 Cell line (Hedgehog Pathway)
Artikelnummer: BPS-60409
The Gli Reporter - NIH3T3 Cell Line is designed for monitoring the activity of the hedgehog signaling pathway. The hedgehog pathway controls stem cell growth in embryonic and adult tissues and promotes tumor growth in a number of human cancers. The mammalian hedgehog proteins, Sonic Hedgehog (Shh), Indian Hedgehog...
| Schlagworte: | Gli cell line, Hedgehog reporter, |
| Anwendung: | Hedgehog pathway activity monitoring |
3.471,00 €
CRE/CREB Reporter (Luc) - HEK293 Cell Line (cAMP/PKA...
Artikelnummer: BPS-60515
The cAMP/PKA Signaling Pathway CRE/CREB Reporter (Luc) - HEK293 Cell Line contains a firefly luciferase gene under the control of multimerized cAMP response element (CRE) stably integrated into HEK293 cells. Elevation of the intracellular cAMP level activates cAMP response element binding protein (CREB) to bind CRE...
| Schlagworte: | CRE cell line, CREB cell line, luciferase reporter, |
| Anwendung: | cAMP/PKA Signaling Pathway pathway monitoring |
| Wirt: | Human cells |
2.960,00 €
PD-L1 - CHO Recombinant Cell Line
Artikelnummer: BPS-60543
Recombinant CHO-K1 cells constitutively expressing human PD-L1 (Programmed Cell Death 1 Ligand 1, CD274, B7 homolog 1 (B7- H1), GenBank accession #NM_014143).
| Schlagworte: | Programmed Cell Death 1 Ligand 1, PDL1, PD-L1, B7 homolog 1, B7H1, B7-H1, CD274, PDCD1L1, |
| Anwendung: | Binding affinity screening, biological assays |
| Spezies-Reaktivität: | human |
7.017,00 €
GITR / NF-kappaB-Luciferase Reporter (Luc) - Jurkat Cell...
Artikelnummer: BPS-60546
This cell line expresses a surface human GITR (glucocorticoid-induced TNFR family related gene, TNFRSF18, CD357) and an NF-kappaB luciferase reporter construct that are stably integrated into the genome of Jurkat T-cells. The firefly luciferase gene is controlled by 4 copies of NF-kappaB response element located...
| Schlagworte: | AITR, CD357, TNFRSF18, Activation-inducible TNFR family receptor, Glucocorticoid-induced TNFR-related protein, Tumor... |
| Anwendung: | NF-kB signaling activity monitoring, GITRL response |
| Spezies-Reaktivität: | human |
12.574,00 €
hERG (Kv11.1) - HEK293 Recombinant Cell line
Artikelnummer: BPS-60619
Human ERG channel has been stably expressed in HEK293 cell line and its expression was confirmed by Western blotting. The channel activity of hERG was characterized by a fluorescence-based assay using thallium influx as a surrogate indicator of potassium ion channel activity coupled with a thallium-sensitive...
| Schlagworte: | ERG, H-ERG, hERG1, KCNH2, ERG-1, hERG-1, Eag homolog, Eag-related protein 1, Ether-a-go-go-related protein 1,... |
| Spezies-Reaktivität: | human |
2.609,00 €
NF-kappaB Luciferase Reporter A549 Cell Line
Artikelnummer: BPS-60625
NF-kappaB luciferase reporter construct is stably integrated into the genome of A549 cells. The firefly luciferase gene is controlled by 4 copies of NF-kappaB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-kappaB transcription factors bind to the DNA...
| Schlagworte: | NF-kappaB cell line, NFkappaB cell line, luciferase reporter, NF-kB cell line, NFkB cell line, |
| Anwendung: | NF-kappaB activity monitoring, luminescence readout |
2.747,00 €
TGFbeta/Activin A-Responsive Luciferase Reporter HEK293...
Artikelnummer: BPS-60653
The TGFbeta/SMAD Signaling Pathway SBE Reporter - HEK293 Cell Line contains a firefly luciferase gene under the control of SMAD-responsive elements stably integrated into HEK293 cells. This cell line is validated for its response to the stimulation of human TGF1 and to treatment with an inhibitor of the TGF/SMAD...
| Schlagworte: | SBE cell line, TGFbeta reporter, SMAD reporter, luciferase reporter, |
| Anwendung: | TGF signaling pathway activity monitoring, activator and inhibitor screening |
| Wirt: | HEK293 |
| Spezies-Reaktivität: | human |
5.194,00 €
GAL4 Reporter (Luc)-HEK293 cell Line (Glucocorticoid...
Artikelnummer: BPS-60655
The Glucocorticoid Receptor Pathway GAL4 Reporter (Luc) - HEK293 Cell Line contains a firefly luciferase gene under the control of glucocorticoid receptor ligand binding domain that is fused to the DNA binding domain (DBD) of GAL4 (GAL4 DBD-GR) stably integrated into HEK293 cells. This fusion construct activates...
| Schlagworte: | GAL4, Glucocorticoid Receptor, |
| Anwendung: | Monitor glucocorticoid signaling pathway activity, screening |
| Wirt: | human cells |
| Spezies-Reaktivität: | human |
12.905,00 €
CD137/NF-kappaB Reporter - HEK293 Recombinant Cell Line
Artikelnummer: BPS-79289
Recombinant HEK293 cell line expressing a full length human CD137 (NM_003811). The NF-kappaB luciferase reporter construct is stably integrated into the genome. The firefly luciferase gene is controlled by 4 copies of NF-kappaB response element located upstream of the TATA promoter. Following activation by human...
| Schlagworte: | CD137, 4-1BB, |
| Anwendung: | CD137 signaling activator / inhibitor screening (cellular context), CD137 characterization |
| Spezies-Reaktivität: | human |
13.502,00 €
WM1366 Viable Cells
Artikelnummer: WM1366-01-0001
Cells are sterile, validated by short tandem repeat profiling, and are tested as negative for mycoplasma. It is recommended that cell lines are tested for mycoplasma contamination and short tandem repeat (STR) profiling every 10 passages or each time a frozen seed stock is made. See cell culture protocol for...
| Anwendung: | Genetic studies, xenograft production, drug testing, drug target discovery |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 1.568,00 €
WM3629 Viable Cells
Artikelnummer: WM3629-01-0001
Cells are sterile, validated by short tandem repeat profiling, and are tested as negative for mycoplasma. It is recommended that cell lines are tested for mycoplasma contamination and short tandem repeat (STR) profiling every 10 passages or each time a frozen seed stock is made. See cell culture protocol for...
| Anwendung: | Genetic studies, xenograft production, drug testing, drug target discovery |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 1.568,00 €
WM9 Viable Cells
Artikelnummer: WM9-01-0001
Cells are sterile, validated by short tandem repeat profiling, and are tested as negative for mycoplasma. It is recommended that cell lines are tested for mycoplasma contamination and short tandem repeat (STR) profiling every 10 passages or each time a frozen seed stock is made. See cell culture protocol for...
| Anwendung: | Genetic studies, xenograft production, drug testing, drug target discovery |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 1.568,00 €
