Rat LOX-1 (Lectin Like Oxidized Low Density Lipoprotein Receptor 1) CLIA Kit

Rat LOX-1 (Lectin Like Oxidized Low Density Lipoprotein Receptor 1) CLIA Kit
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Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-RTES00365.96 96 assays - -

9 - 20 Werktage*

681,00 €
 
ELISA Type: CLIA. Sensitivity: 18.75 pg/mL. Range: 31.25--2000 pg/mL. Protein function: Receptor... mehr
Produktinformationen "Rat LOX-1 (Lectin Like Oxidized Low Density Lipoprotein Receptor 1) CLIA Kit"
ELISA Type: CLIA. Sensitivity: 18.75 pg/mL. Range: 31.25--2000 pg/mL. Protein function: Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria. [The UniProt Consortium]
Schlagworte: Olr1, Lox1
Hersteller: ELISA Genie
Hersteller-Nr: RTES00365

Eigenschaften

Anwendung: CLIA
Reaktivität: Rat
Format: Solid Phase

Handhabung & Sicherheit

Lagerung: vT
Versand: +4°C (International: +4°C)
Signalwort: Warning
GHS-Piktogramme:
H-Sätze: H315, H319
P-Sätze: P264, P280
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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