MS Mouse IL-23 (Interleukin 23) ELISA Kit

This ELISA kit applies to the in vitro quantitative determination of Mouse IL-23 concentrations in serum, plasma and other biological fluids. Photometric. Detection Range: 7.81~500pg/mL. Sensitivity: 4.69pg/mL. Protein function: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. [The UniProt Consortium] Assay Time: 3.5h. Tested Sample Types: Serum, plasma and other biological fluids