Mouse CASP9 (Caspase 9) ELISA Kit

The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of CASP9 in serum, plasma and other biological fluids. Detection Range: 0.16--10ng/mL. Sensitivity: 0.1ng/mL. Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP- ribose) polymerase (PARP). [The UniProt Consortium]