IL-29 (human) ELISA Kit

Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure., Assay Range: 250 pg/ml - 7.8 pg/ml, Sensitivity: 5.9 pg/ml, Cross reaction: No cross reactivity observed with IFNa2, IL-28A, IL-28B, IFNg, IL-10, IL-24, IP-10, IL-31, IL-34 and GM-CSF, Incubation time: 2h40, Sample Types: Cell culture supernatant, serum or plasma tested, other body fluids suitable, Sample Size: 50 µl Protein function: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression. [The UniProt Consortium]