Human IL-15RA/IL-15 R alpha ELISA Kit

ELISA Type: Sandwich. Detection Range: 7.813-500µg/mL. Sensitivity: 4.688µg/mL. Sample Types: Serum, Plasma. Protein function: High-affinity receptor for interleukin-15 (PubMed:8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. In neutrophils, binds and activates kinase SYK in response to IL15 stimulation (PubMed:15123770). In neutrophils, required for IL15- induced phagocytosis in a SYK-dependent manner (PubMed:15123770). Expression of different isoforms may alter or interfere with signal transduction (PubMed:10480910). [The UniProt Consortium]