ACE2:Spike RBD (SARS-CoV-2) Inhibitor Screening Colorimetric Assay Kit

ACE2:Spike RBD (SARS-CoV-2) Inhibitor Screening Colorimetric Assay Kit
ACE2:Spike RBD (SARS-CoV-2) Inhibitor Screening Colorimetric Assay Kit
   
COVID-19 Forschung
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
BPS-78031 96 rxns - -

3 - 15 Werktage*

756,00 €
 
Coronavirus disease 2019 (COVID-19) increases the risk of developing Acute Respiratory Distress... mehr
Produktinformationen "ACE2:Spike RBD (SARS-CoV-2) Inhibitor Screening Colorimetric Assay Kit"
Coronavirus disease 2019 (COVID-19) increases the risk of developing Acute Respiratory Distress Syndrome (ARDS), which is often fatal at the late stages of the infection when the SAR-CoV-2 virus causes significant damage to the lungs. As a first step of the viral replication strategy, the virus attaches to the host cell surface before entering the cell. The Spike protein receptor binding domain (RBD) recognizes and attaches to the Angiotensin-Converting Enzyme 2 (ACE2) receptor found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. Drugs targeting the interaction between the Spike protein of SARS-CoV-2 and ACE2 may offer some protection against the viral infection. The ACE2:SARS-CoV-2 Spike (RBD) Inhibitor Screening Colorimetric Assay Kit is designed for screening and profiling inhibitors of this interaction. The key to this kit is the high sensitivity of detection of Fc-tagged Spike protein by HRP-labeled Anti-mouse-Fc. Only a few simple steps on a microtiter plate are required for the assay. First, ACE2 protein is attached to a clear nickel-coated 96-well plate. Next, SARS-CoV-2 Spike-Fc is incubated with ACE2 on the plate. Finally, the plate is treated with HRP-labeled anti-Fc, followed by addition of an HRP substrate to produce color, which can then be measured using a UV/Vis spectrophotometer microplate reader.
Schlagworte: coronavirus, SARS-CoV-2 inhibition kit, ACE2 inhibition kit, SARS Colorimetric kit, Spike RBD kit, covid, covid-19, covid19, Sars-cov-2, sars cov 2, sarscov2
Hersteller: BPS Bioscience
Hersteller-Nr: 78031

Eigenschaften

Anwendung: SARS-CoV-2 Spike RBD/ACE2 binding inhibitor screening
Reaktivität: Human
Format: Solid Phase

Handhabung & Sicherheit

Lagerung: -80°C
Versand: -80°C (International: °C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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