Anti-FFAR4 (GPR120) (N-Term)

Anti-FFAR4 (GPR120) (N-Term)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay15130-1 1 each -

6 - 10 Werktage*

456,00 €
 
GPR120 is a G protein-coupled receptor (GPCR) expressed in adipocytes and pro-inflammatory... mehr
Produktinformationen "Anti-FFAR4 (GPR120) (N-Term)"
GPR120 is a G protein-coupled receptor (GPCR) expressed in adipocytes and pro-inflammatory macrophages that is activated by long chain free fatty acids. The activation of GPR120 results in elevated calcium ion and activation of the ERK cascade. omega-3 Fatty acids, such as docosahexaenoic acid and eicosapentaenoic acid initiate GPR120 signaling resulting in inhibition of toll-like receptor and TNF-alpha inflammatory signaling pathways in a beta-arrestin2/TAB1 dependent manner. The anti-inflammatory effects of GPR120 are indirectly involved with promoting insulin secretion. GPR120 also mediates free fatty acid induced apoptosis inhibition in the enteroendocrin cell line STC-1. Cayman's N-terminal polyclonal antibody detects GPR120 in LoVo and PC3 cell lysates. The predicted size for GPR120 is 42.2 kDa and the observed size is approximately 45 kDa by western blot.Synonyms: Free Fatty Acid Receptor 4, GPCR129, G Protein-Coupled Receptor 120, GT01, O3FAR1, PGR4. Immunogen: Synthetic peptide from the N-terminal region of human FFAR4 (GPR120). Formulation: (Request formulation change), 500 µl of peptide affinity-purified polyclonal antibody. Storage Buffer: PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide. Host: Rabbit. Applications: ELISA and WB. UniProt Accession #: Q5NUL3.
Schlagworte: Anti-Free fatty acid receptor 4, Anti-Free fatty acid receptor 4, Anti-Omega-3 fatty acid receptor 1, Anti-Omega-3 fatty acid receptor 1, Anti-G-protein coupled receptor 120, Anti-G-protein coupled receptor 129, Anti-G-protein coupled receptor 120, Anti-G
Hersteller: Cayman Chemical
Hersteller-Nr: 15130

Eigenschaften

Anwendung: ELISA, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Synthetic peptide from the N-terminal region of human FFAR4 (GPR120)
MW: 45 kD
Format: Solid

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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