Zu "K08425" wurden 37 Artikel gefunden!
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GPR120 Compound A
Artikelnummer: Cay16624-50
GPR120 (free fatty acid receptor 4/FFAR4) is a G protein-coupled receptor expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids. It has been linked to the ability of fatty acids to produce anti-inflammatory effects and to acutely potentiate insulin...
| Schlagworte: | GPR120 cpdA, 3-[2-chloro-5-(trifluoromethoxy)phenyl]-3-azaspiro[5.5]undecane-9-acetic acid |
| Anwendung: | GPR120 agonist |
| CAS | 1599477-75-4 |
| MW: | 405.8 D |
ab 44,00 €
GPR120 Agonist 3
Artikelnummer: TGM-T15413-100mg
Description: GPR120 Agonist 3 (GPR120-IN-1) is a selective agonist of Gpr120 ( logEC50: -7.62). Target: GPR. Smiles: OC(=O)CC1CCC2(CC1)CCN(CC2)c1cc(OC(F)(F)F)ccc1Cl. References: Oh DY, et al. A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice. Nat Med. 2014 Aug,20(8):942-7.
| Schlagworte: | GPR120-IN-1 |
| Anwendung: | GPR120 agonist |
| CAS | 1599477-75-4 |
| MW: | 405.84 D |
ab 37,00 €
GSK137647A
Artikelnummer: TGM-T3171-100mg
Description: GSK137647A (GSK 137647) is a selective agonist of FFA4. Target: GPR. Smiles: COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(C)cc1C. References: Sparks SM. Etal. Bioorg Med Chem Lett. 2014 Jul 15,24(14):3100-3.
| Schlagworte: | GSK 137647 |
| Anwendung: | GPR120 agonist |
| CAS | 349085-82-1 |
| MW: | 305.39 D |
ab 31,00 €
TUG-891
Artikelnummer: TGM-T3433-100mg
Description: TUG-891 is a G protein-coupled receptor (GPCR) expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids. Target: GPR. Smiles: C(OC1=CC=C(CCC(O)=O)C=C1)C2=C(C=CC(F)=C2)C3=CC=C(C)C=C3. References: Hudson BD, et al. The pharmacology of TUG-891, a...
| Schlagworte: | TUG891, TUG 891 |
| Anwendung: | GPR120 agonist |
| CAS | 1374516-07-0 |
| MW: | 364.41 D |
ab 34,00 €
Anti-FFAR4
Artikelnummer: CSB-PA002756.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-Free fatty acid receptor 4, Anti-Omega-3 fatty acid receptor 1, Anti-G-protein coupled receptor 129, Anti-G-protein... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
AH 7614
Artikelnummer: Cay17713-5
Free fatty acid receptor 4 (FFAR4/GPR120) is a G protein-coupled receptor expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids. omega-3 Fatty acids, such as docosahexaenoic acid (Cay-90310) and eicosapentaenoic acid (Cay-90110), initiate FFAR4...
| Schlagworte: | NSC 31171, N-xanthen-9-yl-p-Toluenesulfonamide, 4-methyl-N-9H-xanthen-9-yl-benzenesulfonamide |
| Anwendung: | GPR120 antagonist |
| CAS | 6326-06-3 |
| MW: | 351.4 D |
ab 44,00 €
TUG-891
Artikelnummer: Cay17035-10
TUG-891 is an agonist of free fatty acid receptor 4 (FFAR4/GPR120, EC50s = 0.0436 and 0.0169 µM for the human and mouse receptors, respectively). It is selective for FFAR4 over FFAR1/GPR40 (EC50 = 64.5 µM for the human receptor) and is inactive against FFAR2/GPR43 and FFAR3/GPR41. TUG-891 (1 µM) inhibits...
| Schlagworte: | 4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]-benzenepropanoic acid |
| Anwendung: | GPR120 agonist |
| CAS | 1374516-07-0 |
| MW: | 364.4 D |
ab 47,00 €
FFAR4 (GPR120) Reporter Assay Kit
Artikelnummer: Cay601200-1
Free fatty acid receptor 4 (FFAR4)/GPR120 is a G protein-coupled receptor for long chain fatty acids such as docosahexaenoic acid and eicosapentaenoic acid omega-3 fatty acids. It is involved in the regulation of glucose uptake in adipocytes and mediates anti-inflammatory activity in macrophages. Cayman's FFAR4...
| Schlagworte: | Free Fatty Acid Receptor 4, G Protein-Coupled Receptor 120, GPCR129, GT01, O3FAR1, PGR4 |
| Anwendung: | Cell based assays, HTS, reverse transfection reporter assay |
| Spezies-Reaktivität: | human |
635,00 €
Grifolic Acid
Artikelnummer: Cay17398-500
GPR120 (free fatty acid receptor 4/FFAR4) is a G protein-coupled receptor expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long-chain free fatty acids. It has been linked to the ability of fatty acids to produce anti-inflammatory effects and to acutely potentiate insulin...
| Schlagworte: | 2,4-dihydroxy-6-methyl-3-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]-benzoic acid |
| Anwendung: | Selective partial GPR120 agonist |
| CAS | 80557-12-6 |
| MW: | 372.5 D |
ab 117,00 €
GSK137647A
Artikelnummer: Cay17712-10
GPR120 (Free Fatty Acid Receptor 4, FFAR4) is a G protein-coupled receptor expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids. GSK137647A is a diarylsulfonamide that acts as a selective agonist of GPR120 (EC50s = 0.5, 0.63, and 0.79 µM for human,...
| Schlagworte: | 4-methoxy-N-(2,4,6-trimethylphenyl)-benzenesulfonamide |
| Anwendung: | GPR120 agonist |
| CAS | 349085-82-1 |
| MW: | 305.4 D |
ab 85,00 €
Anti-FFAR4 (GPR120) (C-Term)
Artikelnummer: Cay14265-1
G Protein-Coupled Receptor (GPR120) is a GPCR activated by the presence of long chain free fatty acids and is expressed in adipocytes and pro-inflammatory macrophages. The activation of GPR120 results in elevated Ca2+ and activation of the ERK cascade. omega-3 Fatty acid constituents such as DHA and EPA mediate...
| Schlagworte: | Anti-Free fatty acid receptor 4, Anti-Free fatty acid receptor 4, Anti-Omega-3 fatty acid receptor 1, Anti-Omega-3 fatty... |
| Anwendung: | ELISA, ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
431,00 €
Anti-FFAR4 (GPR120) (Internal)
Artikelnummer: Cay14904-1
GPR120 is a G protein-coupled receptor (GPR) expressed in adipocytes and pro-inflammatory macrophages that is activated by long chain free fatty acids. The activation of GPR120 results in elevated calcium ions and activation of the ERK cascade. omega-3 Fatty acids, such as docosahexaenoic acid and eicosapentaenoic...
| Schlagworte: | Free Fatty Acid Receptor 4, G Protein-Coupled Receptor 120, GPR120, GPR129, O3FAR1, PGR4 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
431,00 €