Anti-FFAR4 (GPR120) (Internal)

Anti-FFAR4 (GPR120) (Internal)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay14904-1 1 each -

6 - 10 Werktage*

324,00 €
 
GPR120 is a G protein-coupled receptor (GPR) expressed in adipocytes and pro-inflammatory... mehr
Produktinformationen "Anti-FFAR4 (GPR120) (Internal)"
GPR120 is a G protein-coupled receptor (GPR) expressed in adipocytes and pro-inflammatory macrophages that is activated by long chain free fatty acids. The activation of GPR120 results in elevated calcium ions and activation of the ERK cascade. omega-3 Fatty acids, such as docosahexaenoic acid and eicosapentaenoic acid initiate GPR120 signaling resulting in inhibition of lipopolysaccharide and TNF-alpha inflammatory signaling pathways in a beta-arrestin2/TAB1 dependant manner. The anti-inflammatory effects of GPR120 are indirectly involved with promoting insulin secretion. GPR120 also mediates free fatty acid induced apoptosis inhibition in the enteroendocrin cell line STC-1. Cayman's internal polyclonal antibody detects GPR120 in LoVo and PC3 cell lysates. The predicted size for GPR120 is 42.2 kDa and the observed size is approximately 40 kDa by western blot. Synonyms: Free Fatty Acid Receptor 4, G Protein-Coupled Receptor 120, GPR120, GPR129, O3FAR1, PGR4. Immunogen: Synthetic peptide from the internal region of human FFAR4 (GPR120). Formulation: 500 µl of peptide affinity-purified antibody. Storage Buffer: PBS, pH 7.2, with 50% glycerol and 0.02 % sodium azide. Host: Rabbit. Applications: ELISA and WB.
Schlagworte: Free Fatty Acid Receptor 4, G Protein-Coupled Receptor 120, GPR120, GPR129, O3FAR1, PGR4
Hersteller: Cayman Chemical
Hersteller-Nr: 14904

Eigenschaften

Anwendung: ELISA, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human
Immunogen: Synthetic peptide from the internal region of human FFAR4 (GPR120)
Format: Solid

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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