Anti-CD10 (human), Azide Free Clone B-E3 [Mouse]

Specificity: Recognises the Common Acute Lymphoblastic Leukemia Antigen (CALLA), a 100 kDa protein, Format: Phosphate-buffered saline. Sterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free, Storage: Store at +2-8°C for 12 months. For longer storage, freeze aliquots, Application Notes: Suitable for Flow Cytometry, IHC. Does not inhibit the mixed lymphocyte culture. Cytotoxic In association with rabbit complement on CD10+ cells Protein function: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991). Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:15283675). Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:2531377, PubMed:2972276). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573). [The UniProt Consortium]