Zu "K01389" wurden 410 Artikel gefunden!
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Neprilysin/CD10 Protein, Human, Recombinant, Biotinylated
Artikelnummer: TGM-TMPY-07038-100ug
Description: Neprilysin/CD10 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 Cells. The accession number is P08473.
| Schlagworte: | CD10 , CALLA , EPN , CMT2T , NEP , SFE , SCA43 |
| MW: | 79.84 kD |
ab 196,00 €
![Elab Fluor(R) 700 Anti-Human CD10 Antibody[HI10a]](https://www.biomol.com/media/image/33/1e/9c/E-AB-F1141M1-20_200x200.jpg "Elab Fluor(R) 700 Anti-Human CD10 Antibody[HI10a]")
Elab Fluor(R) 700 Anti-Human CD10 Antibody[HI10a]
Artikelnummer: E-AB-F1141M1.100
CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B...
| Schlagworte: | Anti-MME, Anti-Neprilysin, Anti-Enkephalinase, Anti-Atriopeptidase, Anti-Skin fibroblast elastase, Anti-Neutral... |
| Anwendung: | FCM |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 122,00 €
Mouse CD10 ELISA Kit
Artikelnummer: ARG81763.96
Protein function: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9....
| Schlagworte: | SFE, NEP, Mme, CD10, Neprilysin, Enkephalinase, Atriopeptidase, Neutral endopeptidase, Skin fibroblast elastase, Neutral... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
1.118,00 €
AHU377 (calcium salt)
Artikelnummer: Cay21473-10
AHU377 is an ethyl ester prodrug from of the neprilysin inhibitor LBQ657 (Cay-19829). It increases plasma levels of atrial natriuretic factor (ANF) in conscious rats and anesthetized dogs when administered at doses of 10 and 30 mg/kg, respectively. AHU377 (30 mg/kg) increases ANF-induced urinary sodium excretion in...
| Schlagworte: | Sacubitril, (alphaR,gammaS)-gamma-[(3-carboxy-1-oxopropyl)amino]-alpha-methyl-[1,1'-biphenyl]-4-pentanoic acid, 4-ethyl... |
| Anwendung: | Neprilysin inhibitor |
| CAS | 1369773-39-6 |
| MW: | 430.5 D |
ab 105,00 €
LBQ657
Artikelnummer: Cay19829-1
LBQ657 is an inhibitor of neprilysin (IC50 = 5 nM). It is selective for neprilysin over angiotensin converting enzyme (ACE) when used at a concentration of 10 µM. LBQ657 inhibits neprilysin cleavage of enkephalin, glutaryl-Ala-Ala-Phe-beta-napthylamide, and atrial natriuretic factor (IC50s = 5, 0.74, and 5.3 nM,...
| Schlagworte: | Sacubitrilat, gammaS-[(3-carboxy-1-oxopropyl)amino]-alphaR-methyl-[1,1'-biphenyl]-4-pentanoic acid |
| Anwendung: | Neprilysin inhibitor |
| CAS | 149709-44-4 |
| MW: | 383.4 D |
ab 53,00 €
Thiorphan
Artikelnummer: Cay15600-5
Thiorphan is an inhibitor of neprilysin (NEP, IC50 = 0.007 µM). It selectivity inhibits NEP over NEP2 (IC50 = 22 µM), as well as angiotensin-converting enzyme (ACE) and endothelin-converting enzyme 1 (ECE1, Kis = >0.1 and >10 µM, respectively, in cell-free assays). Thiorphan (10 µM) increases bradykinin-induced...
| Schlagworte: | DL-Thiorphan, N-[2-(mercaptomethyl)-1-oxo-3-phenylpropyl]-glycine |
| Anwendung: | Potent neprilysin inhibitor |
| CAS | 76721-89-6 |
| MW: | 253.3 D |
ab 97,00 €
LCZ696
Artikelnummer: Cay23425-10
LCZ696 is a dual angiotensin II receptor antagonist and neprilysin inhibitor that is a combination of the nonpeptide angiotensin II receptor antagonist valsartan (Cay-14178) and AHU377 (Cay-21473), a prodrug of LBQ657 (Cay-19829), which is an inhibitor of the zinc metallopeptidase neprilysin., LCZ696 (2-60 mg/kg)...
| Schlagworte: | N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine compd. with alpha-ethyl... |
| Anwendung: | Angiotensin II receptor antagonist, neprilysin inhibitor |
| CAS | 936623-90-4 |
| MW: | 916 D |
ab 58,00 €
Phosphoramidon (sodium salt)
Artikelnummer: Cay15113-1
Neprilysin (NEP) and NEP2 are membrane-bound zinc metalloproteases. Phosphoramidon is a natural and potent inhibitor of NEP and NEP2, with Ki values of 2 nM for both enzymes. It is also a weak inhibitor of the related zinc metalloprotease endothelin-converting enzyme (Ki = 3.5 µM). Phosphoramidon has little or no...
| Schlagworte: | N-[N-[[(6-deoxy-a-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl]-L-tryptophan, disodium salt |
| Anwendung: | NEP / NEP2 inhibitor |
| CAS | 164204-38-0 |
| MW: | 589.5 D |
ab 133,00 €
Omapatrilat
Artikelnummer: Cay31738-1
Omapatrilat is an orally bioavailable angiotensin-converting enzyme (ACE) and neprilysin (NEP) inhibitior (IC50s = 1.7 and 5.3 nM, respectively, for the human enzymes). It inhibits the pressor response induced by angiotensin I (Cay-24737) in normotensive rats (ED50 = 0.07 µmol/kg) and lowers mean arterial pressure...
| Schlagworte: | BMS-186716,... |
| Anwendung: | Neprilysin inhibitor, ACE inhibitor |
| CAS | 167305-00-2 |
| MW: | 408.5 D |
ab 69,00 €
Anti-MME
Artikelnummer: ATA-HPA052583.25
Protein function: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991). Able to cleave...
| Schlagworte: | Anti-SFE, Anti-MME, Anti-NEP, Anti-EPN, Anti-CD10, Anti-CALLA, Anti-Neprilysin, Anti-Enkephalinase, Anti-Atriopeptidase,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 264,00 €
Sacubitril hemicalcium salt
Artikelnummer: TGM-T4200-10mg
Description: Sacubitril hemicalcium salt (AHU377 calcium salt) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696. Sacubitril hemicalcium salt is a prodrug of LBQ657, which is an inhibitor of the zinc metallopeptidase neprilysin. Neprilysin...
| Schlagworte: | AHU377 calcium salt, AHU-377 (hemicalcium salt) |
| Anwendung: | Neprilysin inhibitor |
| CAS | 1369773-39-6 |
| MW: | 861.06 D |
ab 32,00 €
Anti-CD10, clone SP179
Artikelnummer: ARG52667.100
Protein function: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9....
| Schlagworte: | Anti-MME, Anti-SFE, Anti-NEP, Anti-EPN, Anti-CD10, Anti-CALLA, Anti-Neprilysin, EC=3.4.24.11, Anti-Enkephalinase,... |
| Anwendung: | IHC (paraffin), WB, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
625,00 €