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![Elab Fluor(R) 700 Anti-Human CD10 Antibody[HI10a]](https://www.biomol.com/media/image/33/1e/9c/E-AB-F1141M1-20_200x200.jpg "Elab Fluor(R) 700 Anti-Human CD10 Antibody[HI10a]")
Elab Fluor(R) 700 Anti-Human CD10 Antibody[HI10a]
Artikelnummer: E-AB-F1141M1.100
CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B...
| Schlagworte: | Anti-MME, Anti-Neprilysin, Anti-Enkephalinase, Anti-Atriopeptidase, Anti-Skin fibroblast elastase, Anti-Neutral... |
| Anwendung: | FCM |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 122,00 €
CD10/MME, His, Mouse
Artikelnummer: GSC-Z06049-100
CD10 is an endopeptidase that degrades various bioactive peptides in the extracellular matrix. In addition to enzymatic degradation, it affects multiple intracellular signal transduction pathways. CD10 expression has been extensively studied in human epithelial cancers of numerous organs and sites. CD10 expression...
| Schlagworte: | Mme, Neprilysin, Enkephalinase, Atriopeptidase, Skin fibroblast elastase, Neutral endopeptidase 24.11 |
| Ursprungsart: | mouse |
| MW: | 81.1 kD |
ab 376,00 €
CD10/MME, Human
Artikelnummer: GSC-Z05121-100
CD10 is an endopeptidase that degrades various bioactive peptides in the extracellular matrix. In addition to enzymatic degradation, it affects multiple intracellular signal transduction pathways. CD10 expression has been extensively studied in human epithelial cancers of numerous organs and sites. CD10 expression...
| Schlagworte: | MME, Neprilysin, Enkephalinase, Atriopeptidase, Skin fibroblast elastase, Neutral endopeptidase 24.11, Common acute... |
| Ursprungsart: | human |
| MW: | 79.83 kD |
ab 497,00 €
CD10/MME, His, Human
Artikelnummer: GSC-Z05122-100
CD10 is an endopeptidase that degrades various bioactive peptides in the extracellular matrix. In addition to enzymatic degradation, it affects multiple intracellular signal transduction pathways. CD10 expression has been extensively studied in human epithelial cancers of numerous organs and sites. CD10 expression...
| Schlagworte: | MME, Neprilysin, Enkephalinase, Atriopeptidase, Skin fibroblast elastase, Neutral endopeptidase 24.11, Common acute... |
| Ursprungsart: | human |
| MW: | 80.9 kD |
ab 376,00 €
Mouse CD10 ELISA Kit
Artikelnummer: ARG81763.96
Protein function: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9....
| Schlagworte: | SFE, NEP, Mme, CD10, Neprilysin, Enkephalinase, Atriopeptidase, Neutral endopeptidase, Skin fibroblast elastase, Neutral... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
1.118,00 €
AHU377 (calcium salt)
Artikelnummer: Cay21473-10
AHU377 is an ethyl ester prodrug from of the neprilysin inhibitor LBQ657 (Cay-19829). It increases plasma levels of atrial natriuretic factor (ANF) in conscious rats and anesthetized dogs when administered at doses of 10 and 30 mg/kg, respectively. AHU377 (30 mg/kg) increases ANF-induced urinary sodium excretion in...
| Schlagworte: | Sacubitril, (alphaR,gammaS)-gamma-[(3-carboxy-1-oxopropyl)amino]-alpha-methyl-[1,1'-biphenyl]-4-pentanoic acid, 4-ethyl... |
| Anwendung: | Neprilysin inhibitor |
| CAS | 1369773-39-6 |
| MW: | 430.5 D |
ab 102,00 €
LBQ657
Artikelnummer: Cay19829-1
LBQ657 is an inhibitor of neprilysin (IC50 = 5 nM). It is selective for neprilysin over angiotensin converting enzyme (ACE) when used at a concentration of 10 µM. LBQ657 inhibits neprilysin cleavage of enkephalin, glutaryl-Ala-Ala-Phe-beta-napthylamide, and atrial natriuretic factor (IC50s = 5, 0.74, and 5.3 nM,...
| Schlagworte: | Sacubitrilat, gammaS-[(3-carboxy-1-oxopropyl)amino]-alphaR-methyl-[1,1'-biphenyl]-4-pentanoic acid |
| Anwendung: | Neprilysin inhibitor |
| CAS | 149709-44-4 |
| MW: | 383.4 D |
ab 50,00 €
Thiorphan
Artikelnummer: Cay15600-5
Thiorphan is an inhibitor of neprilysin (NEP, IC50 = 0.007 µM). It selectivity inhibits NEP over NEP2 (IC50 = 22 µM), as well as angiotensin-converting enzyme (ACE) and endothelin-converting enzyme 1 (ECE1, Kis = >0.1 and >10 µM, respectively, in cell-free assays). Thiorphan (10 µM) increases bradykinin-induced...
| Schlagworte: | DL-Thiorphan, N-[2-(mercaptomethyl)-1-oxo-3-phenylpropyl]-glycine |
| Anwendung: | Potent neprilysin inhibitor |
| CAS | 76721-89-6 |
| MW: | 253.3 D |
ab 93,00 €
LCZ696
Artikelnummer: Cay23425-10
LCZ696 is a dual angiotensin II receptor antagonist and neprilysin inhibitor that is a combination of the nonpeptide angiotensin II receptor antagonist valsartan (Cay-14178) and AHU377 (Cay-21473), a prodrug of LBQ657 (Cay-19829), which is an inhibitor of the zinc metallopeptidase neprilysin., LCZ696 (2-60 mg/kg)...
| Schlagworte: | N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine compd. with alpha-ethyl... |
| Anwendung: | Angiotensin II receptor antagonist, neprilysin inhibitor |
| CAS | 936623-90-4 |
| MW: | 916 D |
ab 56,00 €
Phosphoramidon (sodium salt)
Artikelnummer: Cay15113-1
Neprilysin (NEP) and NEP2 are membrane-bound zinc metalloproteases. Phosphoramidon is a natural and potent inhibitor of NEP and NEP2, with Ki values of 2 nM for both enzymes. It is also a weak inhibitor of the related zinc metalloprotease endothelin-converting enzyme (Ki = 3.5 µM). Phosphoramidon has little or no...
| Schlagworte: | N-[N-[[(6-deoxy-a-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl]-L-tryptophan, disodium salt |
| Anwendung: | NEP / NEP2 inhibitor |
| CAS | 164204-38-0 |
| MW: | 589.5 D |
ab 128,00 €
Omapatrilat
Artikelnummer: Cay31738-1
Omapatrilat is an orally bioavailable angiotensin-converting enzyme (ACE) and neprilysin (NEP) inhibitior (IC50s = 1.7 and 5.3 nM, respectively, for the human enzymes). It inhibits the pressor response induced by angiotensin I (Cay-24737) in normotensive rats (ED50 = 0.07 µmol/kg) and lowers mean arterial pressure...
| Schlagworte: | BMS-186716,... |
| Anwendung: | Neprilysin inhibitor, ACE inhibitor |
| CAS | 167305-00-2 |
| MW: | 408.5 D |
ab 67,00 €
Anti-MME
Artikelnummer: ATA-HPA052583.25
Protein function: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991). Able to cleave...
| Schlagworte: | Anti-SFE, Anti-MME, Anti-NEP, Anti-EPN, Anti-CD10, Anti-CALLA, Anti-Neprilysin, Anti-Enkephalinase, Anti-Atriopeptidase,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 264,00 €