Produkte von Optibodies
Optibodies™ sind eine Reihe von monoklonalen Antikörpern für die Immunhistochemie, die von Nordic Biosite hergestellt werden. Sie wurden entwickelt, um den Anwendern von IHC-Biomarkern in der klinischen Pathologie mehr Qualität und mehr Möglichkeiten zu bieten.
Mehr Informationen unter: www.nordicbiosite.com/about/optibodies
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Anti-PDL1
Artikelnummer: OPT-BSH-4003-1
Programmed cell death ligand 1 (PDL1, CD274) is a type 1 transmembrane protein with role in the regulation of cellular immune responses. PDL1 and its receptor PD-1, interacts and regulating T lymphocyte activation and immune tolerance. Blockade of PD-L1/PD-1 interaction, it enhances the antitumor activity of T...
| Schlagworte: | Anti-B7H1, Anti-B7-H1, Anti-CD274, Anti-PD-L1, Anti-hPD-L1, Anti-B7 homolog 1, Anti-PDCD1 ligand 1, Anti-Programmed death... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 250,00 €
Anti-HER2
Artikelnummer: OPT-BSH-4004-1
ERBB2: v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian). This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth...
| Schlagworte: | Anti-HER2, Anti-ERBB2, Anti-CD340, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 250,00 €
Anti-Calretinin
Artikelnummer: OPT-BSH-4005-1
Calretinin is a calcium-binding protein and it is expressed in neurons and in nervous system. Calretinin is also expressed in mesothelial cells and steroid producing cells eg. Leydig cells and adrenal cortical cells as well as fat cells and some neuroendocrine cells. Calretinin located in the cells to nucleus and...
| Schlagworte: | Anti-CR, Anti-CALB2, Anti-CAB29, Anti-Calretinin, Anti-29 kDa calbindin |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 250,00 €
Anti-CD5
Artikelnummer: OPT-BSH-4006-1
The CD5 antigen is a transmembrane glycoprotein which is expressed on the most mature human T-cells and expression level of CD5 will be increased during T-cell maturation. CD5 is also expressed in a small subset of normal human B-cells as well. CD5 is expressed in most T-cell lymphomas and leukemias and negative...
| Schlagworte: | Anti-CD5, Anti-LEU1, Anti-Lymphocyte antigen T1/Leu-1, Anti-T-cell surface glycoprotein CD5 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 250,00 €
Anti-Caveolin 1
Artikelnummer: OPT-BSH-4009-1
Caveolin-1 is a protein which is major structural component of the cell membrane caveolae. Caveolae is structure of the cell membrane invagination. Caveolin-1 is widely expressed in the normal tissue, eg. muscle tissue, vascular endothelia, fibroblasts and adipocytes. Caveolin-1 is useful in lung marker panel,...
| Schlagworte: | Anti-CAV, Anti-CAV1, Anti-Caveolin-1 |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 250,00 €
Anti-CD44
Artikelnummer: OPT-BSH-4013-1
The CD44 antigen, also referred as homing cell adhesion molecule (HCAM), is a multi-structural and multifunctional cell-surface glycoprotein involved in cell-cell interactions, cell adhesion, and migration. Most tissues are CD44 positive, including astrocyte restricted precursor cells, breast myoepithelial cells,...
| Schlagworte: | Anti-LHR, Anti-CD44, Anti-PGP-I, Anti-PGP-1, Anti-CDw44, Anti-Epican, Anti-HUTCH-I, Anti-ECMR-III, Anti-CD44 antigen,... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 250,00 €
Anti-CD117
Artikelnummer: OPT-BSH-4015-1
CD117 is a cell membrane protein encoded by the c-kit proto-oncogene. CD117 is expressed in mast cells, skin melanocytes and interstitial Cajal cells (ICC). These cells show a strong membrane and cytoplasmic staining. CD117 is also expressed in various epithelia (salivary glands, renal tubular cells etc.). Appendix...
| Schlagworte: | Anti-KIT, Anti-PBT, Anti-SCFR, Anti-CD117, Anti-p145 c-kit, EC=2.7.10.1, Anti-Proto-oncogene c-Kit, Anti-Piebald trait... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 250,00 €
Anti-MSH2
Artikelnummer: OPT-BSH-4018-1
MSH2 (MutS Homologue 2) is one of the five key genes (besides MLH1, PMS1, PMS2, MSH6) of the Mis-Match Repair family (MMR). These genes encode MMR proteins, a group of nuclear enzymes that initiates repair of base-base mismatch, that can occur in DNA replication. MMR nuclear proteins form heterodimers, that bind...
| Schlagworte: | Anti-MSH2, Anti-hMSH2, Anti-MutS protein homolog 2, Anti-DNA mismatch repair protein Msh2 |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 250,00 €
Anti-MUM1
Artikelnummer: OPT-BSH-4019-1
MUM1 is a nuclear transcriptional factor (IRF4 or Multiple Myeloma 1 ) and is expressed in final step of intragerminal center B cell differentiation and in post-germinal center B cells. MUM1 is usually mutually exclusive with BCL6 in nonneoplastic tissue. Nuclear expression is present also in a subpopulation of...
| Schlagworte: | Anti-IRF4, Anti-MUM1, Anti-LSIRF, Anti-IRF-4, Anti-NF-EM5, Anti-Multiple myeloma oncogene 1, Anti-Interferon regulatory... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 250,00 €
Anti-TTF1
Artikelnummer: OPT-BSH-4020-1
Thyroid transcription factor, also called thyroid specific enhancer binding nuclear protein (38 kDa), that regulates transcription activity of thyroid (thyroglobulin, thyroid peroxidase, sodium-iodide transport protein, calcitonin and MHC class I) and lung (surfactant proteins A, B and C, Clara cell secretory...
| Schlagworte: | Anti-NKX2A, Anti-TTF-1, Anti-T/EBP, Anti-Homeobox protein Nkx-2.1, Anti-Thyroid nuclear factor 1, Anti-Thyroid... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 250,00 €
Anti-CD8
Artikelnummer: OPT-BSH-5001-1
CD8 T cell surface antigen belongs to the type I membrane protein and it is heterodimer of an alpha and a beta chain linked by two disulfide bonds. CD8 positive T-lymphocytes are cytotoxic cells and it thought to play a role in the process of T-cell mediated killing. CD8 antibody is useful for classification of...
| Schlagworte: | Anti-MAL, Anti-CD8a, Anti-CD8A, Anti-T-cell surface glycoprotein CD8 alpha chain, Anti-T-lymphocyte differentiation... |
| Anwendung: | IHC (paraffin), IHC (frozen) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 250,00 €
Anti-CD14
Artikelnummer: OPT-BSH-7019-1
CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial...
| Schlagworte: | Anti-CD14 |
| Anwendung: | IHC (paraffin), IHC (frozen) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 250,00 €