Produkte von Innaxon

Innaxon

Innaxon ist ein Unternehmen mit Sitz in Tewkesbury, Vereinigtes Königreich, das sich auf angeborene Immunität, Toll-like Rezeptor (TLR)-Agonisten und niedermolekulare Inhibitoren konzentriert. Innaxon entwickelt und produziert definierte "Immunoceuticals" von höchster Aktivität und Reinheit für präklinische Forschungs- und Entwicklungsanwendungen für Impfstoffadjuvantien und Immuntherapie. Die einzigartigen biologischen und synthetischen TLR-Liganden von Innaxon sind gut charakterisierte und wirksame biologische Reaktionsmodifikatoren für unangemessene oder unverhältnismäßige Immunreaktionen.

Mehr Informationen unter: www.adipogen.com/innaxon

Zu den Katalogen von Innaxon

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Lipid A from E. coli R515 (Re) TLRpure Sterile Solution
Lipid A from E. coli R515 (Re) TLRpure Sterile Solution

Artikelnummer: IAX-100-004-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.1-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4), a member of the highly...
Schlagworte: Lipid A derived from E. coli R515 (Re) LPS (biosynthetic)
Anwendung: TLR4 activator
ab 156,00 €
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LPS from S. minnesota R7 (Rd1) TLRpure Sterile Solution
LPS from S. minnesota R7 (Rd1) TLRpure Sterile Solution

Artikelnummer: IAX-100-018-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Schlagworte: Lipopolysaccharide (LPS) from S. minnesota strain R7 (Rd1), R-type (rough/mutant) LPS
Anwendung: TLR4 activator
ab 175,00 €
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LPS from S. enteritidis (S-form) TLRpure Sterile Solution
LPS from S. enteritidis (S-form) TLRpure Sterile Solution

Artikelnummer: IAX-100-019-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Schlagworte: Lipopolysaccharide (LPS) from Salmonella enteritidis, S-type (smooth/wild-type) LPS
Anwendung: TLR4 activator
ab 206,00 €
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LPS from S. minnesota (S-form) TLRpure Sterile Solution
LPS from S. minnesota (S-form) TLRpure Sterile Solution

Artikelnummer: IAX-100-020-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Schlagworte: Lipopolysaccharide (LPS) from Salmonella minnesota, S-type (smooth/wild-type) LPS
Anwendung: TLR4 activator
ab 175,00 €
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ODN 2216 (Type A) Endotoxin-free (sterile)
ODN 2216 (Type A) Endotoxin-free (sterile)

Artikelnummer: IAX-200-005-C100

3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2243 (Cat. No.: IAX-200-205).
Schlagworte: CpG ODN TLR9 Agonist: A Type (species: human and rodent)
Anwendung: TLR9 activator
MW: 6644 D
ab 218,00 €
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LPS from E. coli O8:K27 (S-form) TLRpure Sterile Solution
LPS from E. coli O8:K27 (S-form) TLRpure Sterile Solution

Artikelnummer: IAX-100-006-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Schlagworte: Lipopolysaccharide (LPS) from E. coli O8:K27, S-type (smooth/wild-type) LPS
Anwendung: TLR4 activator
ab 157,00 €
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LPS from E. coli R515 (Re) TLRpure Sterile Solution
LPS from E. coli R515 (Re) TLRpure Sterile Solution

Artikelnummer: IAX-100-007-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Schlagworte: Lipopolysaccharide (LPS) from E. coli strain R515 (Re), R-type (rough/mutant) LPS
Anwendung: TLR4 activator
ab 175,00 €
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LPS from S. minnesota R595 (Re) TLRpure Sterile Solution
LPS from S. minnesota R595 (Re) TLRpure Sterile Solution

Artikelnummer: IAX-100-008-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Schlagworte: Lipopolysaccharide (LPS) from S. minnesota strain R595 (Re), R-type (rough/mutant) LPS
Anwendung: TLR4 activator
ab 175,00 €
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LPS from E. coli J5 (Rc) TLRpure Sterile Solution
LPS from E. coli J5 (Rc) TLRpure Sterile Solution

Artikelnummer: IAX-100-014-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Schlagworte: Lipopolysaccharide (LPS) from E. coli strain J5 (Rc), R-type (rough/mutant) LPS
Anwendung: TLR4 activator
ab 175,00 €
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LPS from S. minnesota R345 (Rb) TLRpure Sterile Solution
LPS from S. minnesota R345 (Rb) TLRpure Sterile Solution

Artikelnummer: IAX-100-015-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Schlagworte: Lipopolysaccharide (LPS) from S. minnesota strain R345 (Rb), R-type (rough/mutant) LPS
Anwendung: TLR4 activator
ab 175,00 €
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ODN 1585 (Type A) Endotoxin-free (sterile)
ODN 1585 (Type A) Endotoxin-free (sterile)

Artikelnummer: IAX-200-003-C100

3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2218 (Cat. No.: IAX-200-203). Unmethylated CG dinucleotides within particular sequence contexts are...
Schlagworte: CpG ODN TLR9 Agonist: A Type (species: rodent)
Anwendung: TLR9 activator
MW: 6643 D
ab 218,00 €
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iODN (inhibitory ODN) 2088 Endotoxin-free (sterile)
iODN (inhibitory ODN) 2088 Endotoxin-free (sterile)

Artikelnummer: IAX-200-050-3001

3 x 1 mg. Potent sequence of an inhibitory ODN for in vivo use in rodents (50-150 µg per injection): prototype class I, may also affect TLR7 and TLR8 signaling. Negative control: Neutral-ODN (Cat. No.: IAX-200-202).
Schlagworte: Inhibitory ODN (iODN): Class I
Anwendung: TLR9 competitor
MW: 4887 D
ab 179,00 €
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