Produkte von Cayman Chemical

Cayman

Cayman Chemical Company ist ein Biotechunternehmen mit Sitz in Ann Arbor, Michigan, das 1980 von Kirk Maxey, M.D. gegründet wurde. Mit seinen biochemischen Produkten unterstützt Cayman Wissenschaftler*innen weltweit bei der Arbeit in den Forschungsfeldern Krebs, NO Signalling, Neurologie, Apoptose, oxidativer Stress, Endokrinologie und vielen weiteren. Cayman Chemical hat sich hierbei besonders auf die Herstellung von Assay-Kits zum Nachweis von Eicosanoiden, freien Radikalen, zyklischen Nukleotiden, Zytokinen, Hormonen und Stickstoffmonoxid spezialisiert. Neben diesen Kits bietet Cayman Chemical ein breites Angebot an Biochemikalien, darunter Eicosanoiden, NO Reagenzien sowie eine Reihe thematisch verwandter Lipide, Fettsäuren, Enzyme und Antikörper.

Mehr Informationen unter: www.caymanchem.com

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NETosis Assay Kit
NETosis Assay Kit

Artikelnummer: Cay601010-1

Cayman's NETosis Assay Kit provides a simple and fast method for studying the process of NETosis ex vivo. Notably, Cayman's NETosis Assay Kit does not depend upon the DNA component of NETs, as DNA release can occur independently of NETosis. In this kit, primary neutrophils are stimulated to release NETs with either...
Schlagworte: NET, Citrullination
Anwendung: NET generation assay
484,00 €
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beta-Hydroxybutyrate (Ketone Body) Colorimetric Assay Kit
beta-Hydroxybutyrate (Ketone Body) Colorimetric Assay Kit

Artikelnummer: Cay700190-96

beta-Hydroxybutyrate (beta-HB, 3-hydroxybutyric acid) is a "ketone body" which is produced in the liver, mainly from the oxidation of fatty acids, and is exported to peripheral tissues for use as an energy source. The term 'ketone body' refers to three molecules, acetoacetate, beta-HB, and acetone. beta-HB and...
Schlagworte: 3-Hydroxybutyric Acid, beta-HB
Anwendung: beta-HB measurement
352,00 €
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TBARS (TCA Method) Assay Kit
TBARS (TCA Method) Assay Kit

Artikelnummer: Cay700870-96

Lipid peroxidation is a well-established mechanism of cellular injury in both plants and animals and is used as an indicator of oxidative stress in cells and tissues. Lipid peroxides, derived from PUFAs, are unstable and decompose to form a complex series of compounds, which include reactive carbonyl compounds, such...
Schlagworte: Thiobarbituric Acid Reactive Substances (TCA Method)
Anwendung: Lipid peroxidation assay
234,00 €
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Glutathione Assay Kit
Glutathione Assay Kit

Artikelnummer: Cay703002-96

Cayman's GSH assay kit utilizes a carefully optimized enzymatic recycling method, using glutathione reductase for the quantification of GSH. The sulfhydryl group of GSH reacts with DTNB (5,5'-dithio-bis-2-nitrobenzoic acid, Ellman's reagent) and produces a yellow colored 5-thio-2-nitrobenzoic acid (TNB). The mixed...
Schlagworte: GSH Assay Kit
Anwendung: GSH quantification
ab 360,00 €
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Glutathione Peroxidase Assay Kit
Glutathione Peroxidase Assay Kit

Artikelnummer: Cay703102-96

Glutathione peroxidase (GPX) catalyzes the reduction of hydroperoxides, including hydrogen peroxides, by reduced glutathione and functions to protect the cell from oxidative damage. With the exception of phospholipid-hydroperoxide GPX, a monomer, all of the GPX enzymes are tetramers of four identical subunits. Each...
Schlagworte: GPX Assay Kit
Anwendung: GTx activity detection
ab 444,00 €
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Superoxide Dismutase Assay Kit
Superoxide Dismutase Assay Kit

Artikelnummer: Cay706002-96

Significant amounts of superoxide dismutase (SOD) in cellular and extracellular environments are crucial for the prevention of diseases linked to oxidative stress. Mutations in SOD account for approximately 20% of familial amyotrophic lateral sclerosis (ALS) cases. SOD also appears to be important in the prevention...
Schlagworte: SOD Assay Kit
Anwendung: SOD detection
ab 352,00 €
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Catalase Assay Kit
Catalase Assay Kit

Artikelnummer: Cay707002-96

Catalase (EC 1.11.1.6, 2H2O2 oxidoreductase) is an ubiquitous antioxidant enzyme that is present in most aerobic cells. Catalase (CAT) is involved in the detoxification of hydrogen peroxide (H2O2), a reactive oxygen species (ROS), which is a toxic product of both normal aerobic metabolism and pathogenic ROS...
Schlagworte: CAT
Anwendung: Catalase activity determination
ab 422,00 €
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Antioxidant Assay Kit
Antioxidant Assay Kit

Artikelnummer: Cay709001-96

Cayman's Antioxidant Assay can be used to measure the total antioxidant capacity of plasma, serum, urine, saliva, or cell lysates. Aqueous- and lipid-soluble antioxidants are not separated in this protocol, thus the combined antioxidant activities of all its constituents including vitamins, proteins, lipids,...
Anwendung: Antioxidant capacity determination
360,00 €
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Nitrate/Nitrite Colorimetric Assay Kit
Nitrate/Nitrite Colorimetric Assay Kit

Artikelnummer: Cay780001-192

Cayman's Nitrate/Nitrite Colorimetric Assay Kit provides an accurate and convenient method for measurement of total and individual nitrate and nitrite concentrations in a simple two-step process utilizing nitrate and nitrite standards. The first step is the conversion of nitrate to nitrite utilizing nitrate...
Schlagworte: Nitric Oxide Metabolite Detection Kit
Anwendung: Nitrate detection, Nitrite detection
291,00 €
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Y-27632 (hydrochloride)
Y-27632 (hydrochloride)

Artikelnummer: Cay10005583-10

The ROCK family of Rho-associated serine-threonine protein kinases is known to play an important role in Rho-mediated cell adhesion and smooth muscle contraction. Y-27632 is a potent, ATP-competitive inhibitor of ROCKs including p160ROCK (Ki = 140 nM) and ROCK2 (IC50 = 800 nM). It also inhibits PRK2 with an IC50...
Schlagworte: 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-trans-cyclohexanecarboxamide, dihydrochloride
Anwendung: ROCK inhibitor
CAS 129830-38-2
MW: 320.3 D
ab 77,00 €
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BMS309403
BMS309403

Artikelnummer: Cay10010206-5

Fatty acid binding protein 4 (FABP4) is a lipid transport protein that is also known as adipocyte FABP and aP2. In addition to adipocytes, it is also abundant in macrophages, along with FABP5, the epidermal FABP. BMS309403 is a cell-permeable, potent inhibitor of FABP4 that targets the fatty acid-binding pocket (Ki...
Schlagworte: A-FABP Inhibitor, Adipocyte FABP Inhibitor, ALBP Inhibitor, aP2 Inhibitor, FABP4 Inhibitor, Fatty Acid Binding Protein 4...
Anwendung: Cell-permeable, potent FABP4 inhibitor
CAS 300657-03-8
MW: 474.6 D
ab 60,00 €
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SAG
SAG

Artikelnummer: Cay11914-1

Smoothened agonist (SAG) is a chlorobenzothiophene-containing compound which acts as a SMO agonist (EC50 = 3 nM) but inhibits hedgehog signaling at high concentrations (>1 µM). It directly binds to SMO and can block SMO inhibition by cyclopamine. Binding of SAG alters the conformation of SMO, leading to its...
Schlagworte: Smoothened Agonist,...
Anwendung: Smo Agonist
CAS 912545-86-9
MW: 490.1 D
ab 48,00 €
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