Produkte von BPS Bioscience
Sonne, Meer und Wissenschaft: BPS Bioscience aus San Diego, Kalifornien stellt rekombinante Histon-Deacetylasen, Methyltransferasen und Demethylasen sowie weitere Modifikationsenzyme her. Außerdem hat BPS eine große Auswahl an Enzymen und Proteinen für die Wirkstoff- sowie die Immuntherapie-Forschung im Programm. Zusätzlich bietet BPS diverse rekombinante Zelllinien sowie unterschiedliche Kits für biochemische Assays an. Kürzlich wurde das Portfolio darüber hinaus um verschiedene Virus-basierte Tools erweitert.
Mehr Informationen unter: www.bpsbioscience.com
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CBL-B TR-FRET Assay Kit
Artikelnummer: BPS-79575
Human Casitas B-lineage lymphoma proto-oncogene b (CBL-B) is an E3 ubiquitinprotein ligase that functions as a negative regulator of T-cell activation. It is a promising drug target in cancer immunotherapy. The CBL-B TR-FRET Assay Kit is designed to measure CBL-B auto-ubiquitination activity in a homogeneous 384...
| Schlagworte: | UBE1, UBA1, ubcH5b, UBE2D2, E3 ubiquitin-protein ligase CBL-B, RING finger protein 56, CBL, CBLB, HTRF, cblb, |
| Anwendung: | Drug discovery, HTS |
| Spezies-Reaktivität: | human |
3.138,00 €
LysA(TM) Universal PARylation Assay Kit
Artikelnummer: BPS-82123
LysA(TM) Universal PARylation Assay Kit is a sandwich ELISA-based kit designed to measure and quantify the amount of total poly ADP-ribosylation present in cell extracts. The kit comes in a convenient 96-well format and contains all the reagents needed, including a PAR standard that allows to establish a standard...
| Schlagworte: | poly-ADP-ribosylation |
| Anwendung: | Poly-ADP-ribosylation quantification, PARP/PARG inhibitor screening/IC50 determination/validation |
1.603,00 €
NK Cell Expansion Kit
Artikelnummer: BPS-78927
The NK Cell Expansion Kit is suitable for the ex vivo culture and expansion of human natural killer (NK) cells. It contains engineered Growth-Arrested NK Feeder Cells and NK Cell Basal Medium. The Growth-Arrested NK Feeder Cells are K562 cells engineered to express membrane bound IL-21, and other components, to...
| Schlagworte: | Za11, IL-21, Interleukin-21, |
| Anwendung: | PBMC-derived NK cell (freshly isolated / frozen) culturing/expansion |
| Spezies-Reaktivität: | human |
1.317,00 €
ACC-1, active human recombinant protein
Artikelnummer: BPS-50202
Human ACC1 (acetyl-Coenzyme A carboxylase alpha transcript variant 1) (GenBank Accession No. NM_198834), amino acids 1-2383(end) with C-terminal FLAG and His-tags, MW = 270 kDa, expressed in Baculovirus infected Sf9 cell expression system. A 25 µl ACC1 reaction is conducted in a buffer containing 30 mM HEPES (pH...
| Schlagworte: | ACAC, ACC1, ACC-alpha, Acetyl-CoA carboxylase 1, Acetyl-Coenzyme A carboxylase alpha, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Baculovirus |
| Ursprungsart: | human |
| MW: | 271 kD |
898,00 €
IDO2, His-tag Recombinant
Artikelnummer: BPS-71194
Human IDO2, also known as Indoleamine 2,3-dioxygenase 2, GenBank Accession No. NM_194294, a.a. 15-420(end) with an N-terminal His-tag, expressed in the presence of hemin in an E. coli cell expression system. MW = 46 kDa.
| Schlagworte: | IDO-2, Indoleamine 2,3-dioxygenase 2, Indoleamine 2,3-dioxygenase-like protein 1, Indoleamine-pyrrole 2,3-dioxygenase-like... |
| Anwendung: | Enzyme kinetics, substrate specificity, inhibitor screening |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 46 kD |
789,00 €
EGFR (del746-750, T790M, C797S), GST-Tag, His-Tag...
Artikelnummer: BPS-100187
Recombinant human EGFR (epidermal growth factor receptor) encompassing tyrosine kinase domain amino acids 668-1210(end) with a deletion of amino acids 746 to 750 and mutations T790M and C797S. This construct contains an N-terminal GST-tag and a C-terminal His-tag (6xHis). This protein was affinity purified.
| Schlagworte: | ERBB, EC=2.7.10.1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-1,... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Ursprungsart: | human |
| MW: | 87 kD |
796,00 €
MCL1, His-Tag (Rat) Recombinant
Artikelnummer: BPS-101299
Recombinant rat MCL1 (myeloid cell leukemia sequence 1) encompassing amino acids 2-307. This construct contains a N-terminal His-Tag (6xHis). The protein was affinity purified.
| Schlagworte: | Mcl1, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, MCL1 (His-2-307) |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | rat |
| MW: | 34 kD |
518,00 €
PARP1, GST-Tag, PAR-Labeled Recombinant
Artikelnummer: BPS-101774
Recombinant human PARP1 (poly-ADP-ribose) polymerase 1), full length, encompassing amino acids 2-1014(end). This construct contains an N-terminal GST-tag followed by a Thrombin Cleavage site. The recombinant protein was affinity purified and PARylated (poly ADP-ribosylated) in vitro.
| Schlagworte: | poly (ADP-ribose) polymerase 1, poly(ADP-ribosyl)transferase, ADPRT, PARP1, PARP-1, PARP1 (GST-Th-2-1014(end))-(PAR) |
| Anwendung: | SDS-PAGE |
| Ursprungsart: | human |
| MW: | 139 + PAR kD |
628,00 €
ALK2 (ACVR1) (PF197_198L), GST-Tag Recombinant
Artikelnummer: BPS-101935
Recombinant human ALK2 (PF197_198L) (activin receptor-like kinase-2), encompassing amino acids 147-end with a PF197_198L mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.
| Schlagworte: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Ursprungsart: | human |
| MW: | 67 kD |
914,00 €
ALK2 (ACVR1) (Q207D), GST-Tag Recombinant
Artikelnummer: BPS-101936
Recombinant human ALK2 (Q207D) (activin receptor-like kinase-2), encompassing amino acids 147-end with a Q207D mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.
| Schlagworte: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Ursprungsart: | human |
| MW: | 67 kD |
914,00 €
ALK2 (ACVR1) (Q207E), GST-Tag Recombinant
Artikelnummer: BPS-101937
Recombinant human ALK2 (Q207E) (activin receptor-like kinase-2), encompassing amino acids 147-end with a Q207E mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active
| Schlagworte: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Ursprungsart: | human |
| MW: | 67 kD |
914,00 €
HDAC11 Recombinant
Artikelnummer: BPS-50021
Human HDAC11 (full length) (GenBank Accession No. NM_024827) untagged, MW= 39.6 kDa, expressed in baculovirus expression system.
| Schlagworte: | HD11, HDAC11, Histone deacetylase 11, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 39,6 kD |
650,00 €
