Anti-phospho-PTEN (Ser294) (PTEN, MMAC1, TEP1, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatas

Anti-phospho-PTEN (Ser294) (PTEN, MMAC1, TEP1, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatas
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
040607.200 200 µl - -

3 - 19 Werktage*

728,00 €
 
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at... mehr
Produktinformationen "Anti-phospho-PTEN (Ser294) (PTEN, MMAC1, TEP1, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatas"
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. Applications: Suitable for use in Dot Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Dot blot 1:500, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Schlagworte: Anti-phospho-PTEN, Anti-phospho-MMAC1, EC=3.1.3.48, EC=3.1.3.16, EC=3.1.3.67, Anti-phospho-Phosphatase and tensin homolog, Anti-phospho-Mutated in multiple advanced cancers 1, Anti-phospho-Phosphatidylinositol 3,4
Hersteller: United States Biological
Hersteller-Nr: 040607

Eigenschaften

Anwendung: ELISA, Dot Blot
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Phospho-PTEN-S294 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S294 of human PTEN.
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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