Zu "K01110" wurden 179 Artikel gefunden!
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Anti-PTEN / Phosphatase and tensin
Artikelnummer: NSJ-FY12369
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. The PTEN antibody targets Phosphatase and tensin homolog, a dual-specificity phosphatase encoded by the PTEN gene. This enzyme is one of the most frequently mutated tumor suppressors in human cancer and plays a crucial role in regulating cell...
| Schlagworte: | Anti-PTEN, Anti-Phosphatase and tensin homolog, Anti-Inositol polyphosphate 3-phosphatase, Anti-Mutated in multiple... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-PTEN
Artikelnummer: NSJ-R33288-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1, MMAC1, TEP1
| Schlagworte: | Anti-PTEN, Anti-Phosphatase and tensin homolog, Anti-Inositol polyphosphate 3-phosphatase, Anti-Mutated in multiple... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse |
836,00 €
Anti-Recombinant PTEN, clone 5A1
Artikelnummer: E-AN301026L.100
Phosphatase and tensin homolog(PTEN) Homo sapiens This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain...
| Schlagworte: | Anti-PTEN, Anti-Phosphatase and tensin homolog, Anti-Inositol polyphosphate 3-phosphatase, Anti-Mutated in multiple... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Anti-Phospho-PTEN (Ser380) Monoclonal Recombinant Antibody
Artikelnummer: E-AN300147L.100
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein...
| Schlagworte: | PTEN, MMAC1, Phosphatase and tensin homolog, Inositol polyphosphate 3-phosphatase, Mutated in multiple advanced cancers 1,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 182,00 €
Anti-PTEN Rabbit (Clone RM511)
Artikelnummer: Cay42778-100
Phosphatase and tensin homolog (PTEN) is a tumor suppressor with roles in cell division, cell migration, and apoptosis. It is ubiquitously expressed and localized to the cytosol and nucleus where it dephosphorylates phosphatidylinositol-(3,4,5)-triphosphate (PIP3) to phosphatidylinositol-(3,4)-diphosphate (PIP2) to...
| Schlagworte: | MMAC1, Mutated in Multiple Advanced Cancers 1, Phosphatase and Tensin Homolog, TEP1 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
554,00 €
Shikonin
Artikelnummer: Cay14751-5
Shikonin is a naturally occurring naphthoquinine isolated from the dried root of L. erythrorhizon, an herb used in traditional Chinese medicine. It increases glucose uptake by adipocytes and myocytes and inhibits the activity of phosphatase and tensin homolog (PTEN, IC50 = 2.7 µM). It inhibits glycolysis in cancer...
| Schlagworte: | C.I. 75535, Isoarnebin 4, NSC 252844, 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-penten-1-yl]-1,4-naphthalenedione |
| Anwendung: | PTEN inhibitor |
| CAS | 517-89-5 |
| MW: | 288.3 D |
ab 49,00 €
bpV(HOpic) (potassium salt)
Artikelnummer: Cay14433-5
bpV(HOpic) is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 14 nM). It also inhibits the vascular endothelial PTP, PTP-beta (IC50 = 4.9 µM), and PTP-1betaB (IC50 = 25.3 µM). At 15 µM, bpV(HOpic) has been shown to protect...
| Schlagworte: | Bisperoxovanadium(HOpic), (5-hydroxy-2-pyridinecarboxylato-kappaN1,kappaO2)oxodiperoxy-vanadate(2-), dipotassium |
| Anwendung: | PTP inhibitor |
| CAS | 722494-26-0 |
| MW: | 347.2 D |
ab 110,00 €
VO-OHpic (hydrate)
Artikelnummer: Cay10009965-1
VO-OHpic is a specific inhibitor of phosphatase and tensin homolog (PTEN, IC50 = 35 nM in vitro). Through this action, it increases cellular phosphatidylinositol 3,4,5-trisphosphate (PIP3) levels, phosphorylation of Akt, and glucose uptake in adipocytes. In mice, VO-OHpic (10 µg/kg, i.p.) decreases left ventricular...
| Schlagworte: | (OC-6-45)-aqua(3-hydroxy-2-pyridinecarboxylato-kappaN1,kappaO2)[3-(hydroxy-kappaO)-2-pyridinecarboxylato(2-)-kappaO2]oxo-v... |
| Anwendung: | PTEN inhibitor |
| CAS | 476310-60-8 |
| MW: | 415.2 D |
ab 50,00 €
Anti-PTEN
Artikelnummer: A300-701A-T
Protein function: Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate,...
| Schlagworte: | Anti-PTEN, Anti-MMAC1, Anti-Phosphatase and tensin homolog, Anti-Mutated in multiple advanced cancers 1,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
bpV(pic) (potassium hydrate)
Artikelnummer: Cay14434-5
bpV(pic) is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 31 nM). It also inhibits the vascular endothelial PTP, PTP-beta (IC50 = 12.7 µM), and PTP-1betaB (IC50 = 61 µM). bpV(pic) is also known to be an insulin mimetic...
| Schlagworte: | Bisperoxovanadium(pic), (PB-7-23-111'1'4)-oxodiperoxy(2-pyridinecarboxylato-kappaN1,kappaO2)-vanadate(2-), dipotassium,... |
| Anwendung: | PTP inhibitor |
| CAS | 148556-27-8 |
| MW: | 367.3 D |
ab 116,00 €
SF1670
Artikelnummer: Cay15368-1
Phosphatase and tensin homology on chromosome 10 (PTEN) functions as a key regulatory enzyme in many signal transduction pathways by dephosphorylating proteins and lipids including Akt and phosphatidylinositol 3,4,5-trisphosphate (PIP3). SF1670 specifically binds to the active site of PTEN inhibiting its activity...
| Schlagworte: | N-(9,10-dihydro-9,10-dioxo-2-phenanthrenyl)-2,2-dimethyl-propanamide |
| Anwendung: | PTEN inhibitor |
| CAS | 345630-40-2 |
| MW: | 307.4 D |
ab 93,00 €
PTEN (human recombinant)
Artikelnummer: Cay10009746-50
Phosphatase and tensin homology on chromosome 10 (PTEN) functions as a key regulatory enzyme in many signal transduction pathways by dephosphorylating proteins and lipids such as AKT and phosphatidylinositol 3,4,5-trisphosphate (PIP3). PTEN interacts with many other proteins to regulate cell division and migration,...
| Schlagworte: | PTEN, MMAC1, Phosphatase and tensin homolog, Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1,... |
| Anwendung: | Enzyme activity |
| MW: | 50,8 kD |
677,00 €