Anti-vPARP

Anti-vPARP
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A301-953A-T 10 µl (10 µg) -

2 - 8 Werktage*

164,00 €
A301-953A 100 µl (100 µg) -

2 - 8 Werktage*

588,00 €
 
PARP4 (poly(ADP-ribose) polymerase family, member 4) catalyzes the formation of ADP-ribose... mehr
Produktinformationen "Anti-vPARP"
PARP4 (poly(ADP-ribose) polymerase family, member 4) catalyzes the formation of ADP-ribose polymers covalently attached to proteins using NADplus as a substrate. There are 6 mammalian PARP enzymes PARP1, PARP2, PARP3, PARP4/vPARP, PARP5/Tankyrase-1, and PARP6/Tankyrase-2. PARP4 is also known as vault PARP (vPARP) due to its association with the vault particle, a 13MDa cytoplasmic ribonucleoprotein complex whose barrel-shaped structure resembles arched cathedral ceilings. vPARP has also been identified separate from the vault particle. It has been localized to the nuclear pore, mitotic spindle, and cytoplasm. It also has been shown to associate with telomerase activity. Studies of vPARP knockout mice show an increased susceptibility to carcinogen-induced tumorigenesis. vPARP is also known as PARP-related IalphaI-related H5/proline-rich, PH5P, p193, PARPL, VWA5C, VAULT3, ADPRTL1, and KIAA0777.
Schlagworte: Anti-PH5P, Anti-ARTD4, Anti-VPARP, Anti-PARP4, Anti-PARP-4, Anti-ADPRTL1, EC=2.4.2.30, Anti-193 kDa vault protein, Anti-Poly [ADP-ribose] polymerase 4, Anti-Vault poly(ADP-ribose) polymerase, Anti-PARP-related/IalphaI-related H5/proline-rich
Hersteller: Bethyl Laboratories
Hersteller-Nr: A301-953A

Eigenschaften

Anwendung: WB, IP
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human (Erwartet: rhesus monkey, gorilla, chimpanzee, crab-eating macaque, northern white-cheeked gibbon)
Immunogen: synthetic peptide. The epitope recognized by A301-953A-T maps to a region between residue 1400 and 1450 of human vault poly(ADP-ribose) polymerase using the numbering given in entry NP_006428.2 (GeneID 143).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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