- Suchergebnis für K10798
Cookie-Einstellungen
Diese Website benutzt Cookies, die für den technischen Betrieb der Website erforderlich sind und stets gesetzt werden. Andere Cookies, die den Komfort bei Benutzung dieser Website erhöhen, der Direktwerbung dienen oder die Interaktion mit anderen Websites und sozialen Netzwerken vereinfachen sollen, werden nur mit Ihrer Zustimmung gesetzt.
Konfiguration
Technisch erforderlich
Diese Cookies sind für die Grundfunktionen des Shops notwendig.
"Alle Cookies ablehnen" Cookie
"Alle Cookies annehmen" Cookie
Ausgewählter Shop
CSRF-Token
Cookie-Einstellungen
FACT-Finder Tracking
Individuelle Preise
Kundenspezifisches Caching
Session
Währungswechsel
Komfortfunktionen
Diese Cookies werden genutzt um das Einkaufserlebnis noch ansprechender zu gestalten, beispielsweise für die Wiedererkennung des Besuchers.
Facebook-Seite in der rechten Blog - Sidebar anzeigen
Merkzettel
Statistik & Tracking
Endgeräteerkennung
Kauf- und Surfverhalten mit Google Tag Manager
Partnerprogramm
Zu "K10798" wurden 133 Artikel gefunden!
Filter schließen
Filtern nach:
Für die Filterung wurden keine Ergebnisse gefunden!
Artikelnummer: Cay10621-5
Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM,...
Schlagworte: | AZD 2281, Ku-0059436, 4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone |
Anwendung: | PARP1 / PARP2 inhibitor |
CAS | 763113-22-0 |
MW: | 434.5 D |
ab 66,00 €
Artikelnummer: ELK-ELK3564.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PARP4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PARP4. Next,...
Schlagworte: | PH5P, VPARP, ARTD4, PARP-4, 193 kDa vault protein, Poly [ADP-ribose] polymerase 4, Vault poly(ADP-ribose) polymerase,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: ELK-ELK8380.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PARP2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PARP2. Next,...
Schlagworte: | ARTD2, Parp2, Adprt2, PARP-2, ADPRT-2, mPARP-2, pADPRT-2, Poly[ADP-ribose] synthase 2, Poly [ADP-ribose] polymerase 2,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: Cay19782-1
BMN 673 is an orally available poly(ADP-ribose) polymerase (PARP) inhibitor with an IC50 value of 0.57 nM. It similarly binds to PARP1 and PARP2 with Ki values of 1.2 and 0.85 nM, respectively, but has no effect on PARG. BMN 673 selectively targets tumor cells with BRCA1, BRCA2, or PTEN gene mutations and elicits...
Schlagworte: | Talazoparib,... |
Anwendung: | Antineoplastic, PARP inhibitor |
CAS | 1207456-01-6 |
MW: | 380.4 D |
ab 97,00 €
Artikelnummer: BPS-101690
Recombinant human PARP 4 (poly(ADP-ribose) polymerase family member 4), encompassing amino acids 2-700. This construct contains an N-terminal FLAG-Tag. This recombinant protein was affinity purified.
Schlagworte: | PH5P, VPARP, ARTD4, PARP-4, 193 kDa vault protein, Poly [ADP-ribose] polymerase 4, Vault poly(ADP-ribose) polymerase,... |
Anwendung: | PARP studies |
Ursprungsart: | human |
MW: | 80 kD |
415,00 €
Artikelnummer: LKT-N3310.50
A naturally occurring vitamin and a protease inhibitor. Topical nicotinamide has demonstrable preventive activity against photo carcinogenesis in mice by elevating skin nicotinamide-adenine dinucleotide (NAD) content. It also has protective effects against lung and pancreatic carcinogenesis. Niacinamide also...
Schlagworte: | Niacinamide, nicotinic acid amide |
Anwendung: | Protease inhibitor |
CAS | 98-92-0 |
MW: | 122,12 D |
ab 85,00 €
Artikelnummer: BPS-80502
Active human PARP2 (GenBank Accession No. NM_005484), amino-acids 2-583 with N-terminal GST tag, MW = 92 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Schlagworte: | ARTD2, PARP-2, ADPRT2, ADPRT-2, hPARP-2, pADPRT-2, Poly[ADP-ribose] synthase 2, Poly [ADP-ribose] polymerase 2, NAD(+)... |
Anwendung: | Enzyme kinetics, inhibitor screening |
MW: | 92 kD |
861,00 €
Artikelnummer: Cay11505-5
Poly(ADP-ribose) polymerases (PARPs) have diverse roles in cellular processes, including DNA repair and apoptosis. ABT-888 is an orally bioavailable inhibitor of PARP1 and PARP2 (Kis = 5.2 and 2.9 nM, respectively). It enhances apoptosis and autophagy in response to treatments that cause DNA breaks, including...
Schlagworte: | Veliparib, 2-[(2R)-2-methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide, dihydrochloride |
Anwendung: | PARP1 / PARP2 inhibitor |
CAS | 912445-05-7 |
MW: | 317.2 D |
ab 60,00 €
Artikelnummer: Cay14450-1
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. DPQ is a potent inhibitor of PARPs, inhibiting PARP1 with an IC50 value of 40 nM. It is approximately 10-fold less potent against PARP2. DPQ can...
Schlagworte: | PARP Inhibitor III, 3,4-dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone |
Anwendung: | PARP inhibitor |
CAS | 129075-73-6 |
MW: | 302.4 D |
ab 76,00 €
Artikelnummer: Cay20842-5
MK-4827 is an orally bioavailable inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2 (IC50s = 3.8 and 2.1 nM, respectively). It inhibits the proliferation of cancer cells carrying the breast cancer mutations BRCA1 and BRCA2 in vitro (IC50 values range from 10-100 nM) and has efficacy alone against a...
Schlagworte: | Niraparib tosylate, 2-[4-(3S)-3-piperidinylphenyl]-2H-indazole-7-carboxamide, 4-methylbenzenesulfonate |
Anwendung: | Antineoplastic |
CAS | 1038915-73-9 |
MW: | 492.6 D |
ab 62,00 €
Artikelnummer: LKT-O4402.5
A potent orally active inhibitor of PARP (Poly(adenosine diphosphate-ribose) polymerase)-1 and PARP-2.
Schlagworte: | AZD2281, KU-0059436 |
Anwendung: | Poly(adenosine diphosphate-ribose) polymerase inhibitor |
CAS | 763113-22-0 |
MW: | 434,47 D |
ab 108,00 €
Artikelnummer: Cay24677-1
AG-14361 is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1, Ki = 6.3 nM for the human enzyme). It inhibits PARP1 activity in permeabilized and intact SW620 cells (IC50s = 29 and 14 nM, respectively). AG-14361 (0.4 µM) potentiates the growth inhibitory effects of temozolomide (Cay-14163) in HCT116, A2480, and...
Schlagworte: | 2-[4-[(dimethylamino)methyl]phenyl]-5,6-dihydro-imidazo[4,5,1-jk][1,4]benzodiazepin-7(4H)-one |
Anwendung: | PARP1 inhibitor |
CAS | 328543-09-5 |
MW: | 320.4 D |
ab 60,00 €