Zu "K10798" wurden 139 Artikel gefunden!
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Olaparib
Artikelnummer: Cay10621-5
Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM,...
| Schlagworte: | AZD 2281, Ku-0059436, 4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone |
| Anwendung: | PARP1 / PARP2 inhibitor |
| CAS | 763113-22-0 |
| MW: | 434.5 D |
ab 66,00 €
![Poly [ADP-ribose] polymerase 2 (PARP2), human, recombinant](https://www.biomol.com/media/image/ab/52/0e/CSB-BP866224HU-1_200x200.jpg "Poly [ADP-ribose] polymerase 2 (PARP2), human, recombinant")
Poly [ADP-ribose] polymerase 2 (PARP2), human, recombinant
Artikelnummer: CSB-BP866224HU.1
Organism: Homo sapiens (Human). Source: Baculovirus. Expression Region: 1-583aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MAARRRRSTG GGRARALNES KRVNNGNTAP EDSSPAKKTR RCQRQESKKM PVAGGKANKD RTEDKQDGMP GRSWASKRVS ESVKALLLKG KAPVDPECTA KVGKAHVYCE GNDVYDVMLN QTNLQFNNNK...
| Schlagworte: | PARP2, ARTD2, ADPRT2, PARP-2, hPARP-2, ADPRT-2, pADPRT-2, Poly[ADP-ribose] synthase 2, Poly [ADP-ribose] polymerase 2,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 71.6 kD |
ab 474,00 €
![Poly [ADP-ribose] polymerase 2 (PARP2), human, recombinant](https://www.biomol.com/media/image/5e/2c/2a/CSB-BP866224HUg6-1_200x200.jpg "Poly [ADP-ribose] polymerase 2 (PARP2), human, recombinant")
Poly [ADP-ribose] polymerase 2 (PARP2), human, recombinant
Artikelnummer: CSB-BP866224HUg6.1
Organism: Homo sapiens (Human). Source: Baculovirus. Expression Region: 1-583aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged and C-terminal 6xHis-tagged. Target Protein Sequence: MAARRRRSTG GGRARALNES KRVNNGNTAP EDSSPAKKTR RCQRQESKKM PVAGGKANKD RTEDKQDGMP GRSWASKRVS ESVKALLLKG KAPVDPECTA KVGKAHVYCE...
| Schlagworte: | PARP2, ARTD2, ADPRT2, PARP-2, hPARP-2, ADPRT-2, pADPRT-2, Poly[ADP-ribose] synthase 2, Poly [ADP-ribose] polymerase 2,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 92.8 kD |
ab 474,00 €
![Poly [ADP-ribose] polymerase 2 (PARP2), human, recombinant](https://www.biomol.com/media/image/5e/0f/c4/CSB-EP866224HU-1_200x200.jpg "Poly [ADP-ribose] polymerase 2 (PARP2), human, recombinant")
Poly [ADP-ribose] polymerase 2 (PARP2), human, recombinant
Artikelnummer: CSB-EP866224HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-583aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MAARRRRSTG GGRARALNES KRVNNGNTAP EDSSPAKKTR RCQRQESKKM PVAGGKANKD RTEDKQDGMP GRSWASKRVS ESVKALLLKG KAPVDPECTA KVGKAHVYCE GNDVYDVMLN QTNLQFNNNK...
| Schlagworte: | PARP2, ARTD2, ADPRT2, PARP-2, hPARP-2, ADPRT-2, pADPRT-2, Poly[ADP-ribose] synthase 2, Poly [ADP-ribose] polymerase 2,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 72.2 kD |
ab 283,00 €
![Poly [ADP-ribose] polymerase 2 (PARP2), partial, human, recombinant](https://www.biomol.com/media/image/c8/c0/1a/CSB-EP866224HU1-1_200x200.jpg "Poly [ADP-ribose] polymerase 2 (PARP2), partial, human, recombinant")
Poly [ADP-ribose] polymerase 2 (PARP2), partial, human,...
Artikelnummer: CSB-EP866224HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 233-583aa. Protein Length: Partial. Tag Info: C-terminal 10xHis-tagged. Target Protein Sequence: QLDLRVQELI KLICNVQAME EMMMEMKYNT KKAPLGKLTV AQIKAGYQSL KKIEDCIRAG QHGRALMEAC NEFYTRIPHD FGLRTPPLIR TQKELSEKIQ LLEALGDIEI AIKLVKTELQ SPEHPLDQHY RNLHCALRPL...
| Schlagworte: | PARP2, ARTD2, ADPRT2, PARP-2, hPARP-2, ADPRT-2, pADPRT-2, Poly[ADP-ribose] synthase 2, Poly [ADP-ribose] polymerase 2,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 41.3 kD |
ab 283,00 €
Protein mono-ADP-ribosyltransferase PARP4 (PARP4),...
Artikelnummer: CSB-EP892136HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 607-1046aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: SSTKAGLQDA SGNLVPLEDV HIKGRIIDTV AQVIVFQTYT NKSHVPIEAK YIFPLDDKAA VCGFEAFING KHIVGEIKEK EEAQQEYLEA VTQGHGAYLM SQDAPDVFTV SVGNLPPKAK VLIKITYITE...
| Schlagworte: | PH5P, ARTD4, VPARP, PARP-4, 193 kDa vault protein, Poly [ADP-ribose] polymerase 4, Vault poly(ADP-ribose) polymerase,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 55.0 kD |
ab 283,00 €
Protein mono-ADP-ribosyltransferase PARP3 (PARP3), human,...
Artikelnummer: CSB-MP017467HU.1
Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 1-533aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal hFc-tagged. Target Protein Sequence: MAPKPKPWVQ TEGPEKKKGR QAGREEDPFR STAEALKAIP AEKRIIRVDP TCPLSSNPGT QVYEDYNCTL NQTNIENNNN KFYIIQLLQD SNRFFTCWNR...
| Schlagworte: | IRT1, ARTD3, PARP-3, hPARP-3, ADPRT-3, pADPRT-3, Poly[ADP-ribose] synthase 3, Poly [ADP-ribose] polymerase 3, NAD(+)... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Mammalian cells |
| Ursprungsart: | human |
| MW: | 90.4 kD |
ab 293,00 €
Anti-PARP2
Artikelnummer: CSB-PA006369.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-PARP2, Anti-ARTD2, Anti-PARP-2, Anti-ADPRT2, Anti-hPARP-2, Anti-ADPRT-2, Anti-pADPRT-2, Anti-Poly[ADP-ribose]... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 106,00 €
Anti-PARP3
Artikelnummer: CSB-PA057327.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PARP3. Antigen Species: Human
| Schlagworte: | Anti-IRT1, Anti-ARTD3, Anti-PARP-3, Anti-hPARP-3, Anti-ADPRT-3, Anti-pADPRT-3, Anti-Poly[ADP-ribose] synthase 3, Anti-Poly... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
Anti-PARP3
Artikelnummer: CSB-PA148428.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PARP3. Antigen Species: Human
| Schlagworte: | Anti-IRT1, Anti-ARTD3, Anti-PARP-3, Anti-hPARP-3, Anti-ADPRT-3, Anti-pADPRT-3, Anti-Poly[ADP-ribose] synthase 3, Anti-Poly... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
Anti-PARP2
Artikelnummer: CSB-PA152331.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-PARP2, Anti-ARTD2, Anti-PARP-2, Anti-ADPRT2, Anti-hPARP-2, Anti-ADPRT-2, Anti-pADPRT-2, Anti-Poly[ADP-ribose]... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
275,00 €
Anti-PARP3
Artikelnummer: CSB-PA285823.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PARP3. Antigen Species: Human
| Schlagworte: | Anti-IRT1, Anti-ARTD3, Anti-PARP-3, Anti-hPARP-3, Anti-ADPRT-3, Anti-pADPRT-3, Anti-Poly[ADP-ribose] synthase 3, Anti-Poly... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €