Anti-UBR5

Anti-UBR5
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R34708-100UG 100 µg - -

3 - 10 Werktage*

755,00 €
 
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s)... mehr
Produktinformationen "Anti-UBR5"
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: E3 ubiquitin protein ligase, HECT domain containing 1, EDD1, HECT1 Protein function: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Involved in maturation and/or transcriptional regulation of mRNA by activating CDK9 by polyubiquitination. May play a role in control of cell cycle progression. May have tumor suppressor function. Regulates DNA topoisomerase II binding protein (TopBP1) in the DNA damage response. Plays an essential role in extraembryonic development. Ubiquitinates acetylated PCK1. Also acts as a regulator of DNA damage response by acting as a suppressor of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of 'Lys-63'- linked histone H2A and H2AX at DNA damage sites, thereby acting as a guard against excessive spreading of ubiquitinated chromatin at damaged chromosomes. [The UniProt Consortium]
Schlagworte: Anti-EDD, Anti-UBR5, Anti-hHYD, EC=6.3.2.-, Anti-Progestin-induced protein, Anti-E3 ubiquitin-protein ligase UBR5, Anti-Hyperplastic discs protein homolog, Anti-E3 ubiquitin-protein ligase, HECT domain-containing 1, UBR5 Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: R34708

Eigenschaften

Anwendung: ELISA (peptide), IHC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Goat
Spezies-Reaktivität: human, rat, mouse, rabbit
Immunogen: Amino acids LAIKTKNFGFV were used as the immunogen for this UBR5 antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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