Anti-UBA3 [R05-6C8] Monoclonal Antibody

UBA3 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression [The Uniprot Consortium]