Anti-Superoxide Dismutase 2 Antibody (SOD2), clone 37CT127.5.11.6

In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Protein function: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. [The UniProt Consortium]