Anti-Smad7

Anti-Smad7
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG20572.50 50 µl - -

6 - 14 Werktage*

551,00 €
 
Protein function: Antagonist of signaling by TGF-beta (transforming growth factor) type 1... mehr
Produktinformationen "Anti-Smad7"
Protein function: Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A- PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. [The UniProt Consortium]
Schlagworte: Anti-SMAD7, Anti-Smad7, Anti-MADH7, Anti-SMAD 7, Anti-hSMAD7, Anti-MAD homolog 7, Anti-MAD homolog 8, Anti-SMAD family member 7, Anti-Mothers against DPP homolog 8, Anti-Mothers against DPP homolog 7, Anti-Mothers against decapentaplegic homolog 8
Hersteller: Arigo Biolaboratories
Hersteller-Nr: ARG20572

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human (Erwartet: mouse, rat)
Immunogen: Synthetic peptides around aa. 12-29 (RLWRSRAPGGEDEEEGAG) and aa. 36-50 (ELRGEGATDSRAHGA) of Human SMAD7. This sequence is 100% or highly conserved between Human and multiple species
MW: 53 kD
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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