Anti-SMAD7

Anti-SMAD7
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
200-401-I16 100 µg - -

6 - 10 Werktage*

819,00 €
 
Anti-SMAD7 Antibody was purified by Protein G chromatography. A BLAST analysis was used to... mehr
Produktinformationen "Anti-SMAD7"
Anti-SMAD7 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-SMAD7 from human, rat, sheep and mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-SMAD7 from other sources has not been determined. Protein function: Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A- PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. [The UniProt Consortium]
Schlagworte: Anti-Smad7, Anti-SMAD7, Anti-MADH7, Anti-hSMAD7, Anti-SMAD 7, Anti-MAD homolog 7, Anti-MAD homolog 8, Anti-SMAD family member 7, Anti-Mothers against DPP homolog 8, Anti-Mothers against DPP homolog 7, Anti-Mothers against decapentaplegic homolog 8
Hersteller: Rockland Immunochemicals
Hersteller-Nr: 200-401-I16

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: SMAD7 peptide.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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